Special Engineer, Cancer Immunotherapy

Oslo University Hospital; Oslo; On-site; NOK 600,000 - 800,000; Full time

Job summary

Oslo University Hospital's Unit for Translational Research, Section of Cell Therapy, seeks a Special Engineer to support clinical trials in cancer immunotherapy. The role involves handling patient samples, isolating immune cells, and evaluating immune responses to vaccines and adoptive therapies.

The successful candidate will document lab procedures, maintain GLP standards, and collaborate with a team of researchers in a state-of-the-art GMP facility.

Qualifications

• MSc or equivalent in Biology.
• Experience with primary T-cell culture, ELISA/ELISPOT, and flow cytometry is required.
• Knowledge of GLP and handling patient samples is essential.
• Experience with transfection, Western blot and microarray would be an advantage.

Responsibilities

• Process patient samples from clinical trial participants.
• Isolate immune cells and assess immune responses (cytokine, phenotype, cytotoxicity).
• Document procedures and maintain lab methods.
• Communicate with study personnel and contribute to lab operations and research development.

Skills

Primary T-cell culture

ELISA/ELISPOT

Flow cytometry

Education

MSc in Biology

Tools

Flow cytometer

ELISA equipment

Job description

At the Unit for Translational Research, Section of Cell Therapy, Oslo University Hospital, Radium Hospital, a position is available for a Special Engineer, with employment starting as soon as possible, before the end of September 2026. Applicants must hold at least an MSc degree in Biology. The appointment is initially until 31 December 2026, with the possibility of extension.
The Section for Cell Therapy is a clinical section that houses one of Europe's largest and most modern GMP facilities for cell products. The section also manufactures products for international industry-sponsored clinical trials. The section employs more than 40 staff members. The focus of its translational research activities is the development of novel cancer immunotherapies, including the preclinical and clinical development and evaluation of improved cancer vaccines and adoptive cell therapies.
http://ous-research.no/home/cellulartherapy/

Oslo University Hospital is a workplace with great diversity. We believe this is crucial for solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions, and weencourage all qualified candidates, regardless of background, to apply!

The work associated with this position involves the processing of patient samples from participants enrolled in clinical trials evaluating novel cancer vaccines and other immunotherapies in both industry-sponsored and academic studies. The analyses include, among other things, the investigation of T-cell responses following immunotherapy treatment, as well as the identification and characterisation of novel cancer antigens recognised by the patient's immune system.
The successful candidate will receive samples from cancer patients, isolate immune cells, assess immune responses (cytokine response, phenotype, cytotoxicity), and conduct further research related to the immune system and biomarkers of treatment response. In addition, the role includes the establishment and documentation of laboratory procedures and methods, as well as regular communication with study personnel involved in clinical trials. The employee will also be responsible for some aspects of laboratory operations and will contribute to research and the development of new therapeutic approaches.

Qualifications

• Applicants must hold a qualification equivalent to an MSc degree in Biology.
• Experience with primary T-cell culture, ELISA or ELISPOT assays, and flow cytometry is required.
• Knowledge of Good Laboratory Practice (GLP) as well as experience working with patient samples or method validation is also essential.
• Experience with transfection, Western blot and microarray technology would be an advantage.

We are seeking a candidate who is accurate, efficient, responsible, flexible, and a strong communicator, with the ability to work effectively as part of a team. Personal suitability and interpersonal skills will be given significant consideration.

Relevant documentation must be attached to the application.

We offer

We offer a secure workplace with a pleasant working environment, supportive colleagues, and a challenging position that provides a high degree of independence within a professionally stimulating and collaborative research environment.

Oslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments. As Scandinavia's largest hospital, we carry out more than 1.2 million patient treatments each year. The hospital has a nationwide responsibility for a number of national and multi-regional assignments, and has several national centers of competence. Oslo University Hospital is responsible for approximately 50 percent of all medical and health care research conducted at Norwegian hospitals, and is a significant role player within the education of a large variety of health care personnel.