Senior Scientist, In vitro Pharmacology

Actithera; Oslo; On-site; NOK 800,000 - 1,000,000; Full time

Job summary

A radiopharmaceutical biotech company in Oslo seeks a skilled Scientist to join their in vitro pharmacology team. The role involves executing in vitro studies, conducting a range of assays, and collaborating with other teams. Candidates should have an MSc or PhD in a related field, hands-on experience with cell culture and pharmacology assays, and a knowledge of radioactive materials. The position offers competitive compensation and the chance to impact patient lives through innovative science.

Benefits

Competitive compensation and benefits package

Opportunity to work at the forefront of radioligand therapeutic discovery

Qualifications

• 2+ years of industry or academic experience.
• Prior experience in radiopharmaceuticals is essential.
• Familiarity with immunohistochemistry assays is considered an advantage.

Responsibilities

• Conduct in vitro experiments including cell culture and various pharmacology assays.
• Collaborate with radiochemistry and pharmacology teams.
• Present experimental results in team meetings.

Skills

Hands-on experience with mammalian cell culture and in vitro pharmacology assays

Strong organizational skills

Excellent communication skills

Ability to handle radioactive materials safely

Education

MSc or PhD in Pharmacology, Cell Biology, Biochemistry

Tools

FACS analyses

Autoradiography

Job description

Position Overview

Actithera is a radiopharmaceutical biotech company, co-headquartered in Oslo and Cambridge, Massachusetts, founded in 2021. The company applies a chemistry-first approach to design next-generation radioligand therapies (RLTs) that deliver potent, tumor-focused radiation while sparing healthy tissue—guided by an isotope-agnostic and platform-enabled strategy to optimize tumor retention and therapeutic index. Actithera’s vision is rooted in precision molecular design and a deeply collaborative culture, with a shared mission to transform the lives of cancer patients through innovative science.

We are seeking a motivated and skilled Scientist to join our in vitro pharmacology team in Oslo. This role focuses on the hands-on execution of in vitro studies to support our radiopharmaceutical discovery programs. The Scientist will perform a broad range of assays to characterize candidate compounds and generate high-quality data that advances our pipeline.

Key Responsibilities

• Conduct in vitro experiments including cell culture, radioligand binding and uptake assays, internalization, efflux, stability, and mechanism-of-action studies.
• Maintain and handle mammalian cell cultures and implement high-quality laboratory practices.
• Execute established protocols and maintain meticulous laboratory records.
• Analyze, and report experimental results, contributing to data packages for internal reviews.
• Collaborate closely with radiochemistry and in vivo pharmacology teams to support appropriate ex vivo readouts and to integrate data into program strategies.
• Present experimental results in team meetings and contribute to scientific publications and IP filings.
• Ensure compliance with laboratory safety standards and radiation protection guidelines.

Qualifications

• MSc or PhD in Pharmacology, Cell Biology, Biochemistry, or related discipline with 2+ years of industry or academic experience.
• Hands-on experience with mammalian cell culture and in vitro pharmacology assays with experience in binding, internalization/efflux, DNA damage and cytotoxicity assays.
• Proven ability to handle radioactive materials safely and in compliance with regulations.
• Prior experience in radiopharmaceuticals is essential.
• Experience with FACS analyses and autoradiography is required; familiarity with immunohistochemistry assays is considered an advantage.
• Strong organizational skills, attention to detail, and ability to deliver reproducible results.
• Team player with excellent communication skills.

What We Offer

• Opportunity to work at the forefront of radioligand therapeutic discovery with a team committed to scientific excellence and patient impact.
• Competitive compensation and benefits package.

Reach out with your resume: [e-mail]