Senior Research Associate Biochemistry

Lonza Group Ltd.; Oss; On-site; Confidential; Full time

Benefits offered by this job

An agile career and dynamic working文化

An inclusive and ethical workplace

Compensation programs that recognize高绩

A variety of benefits dependent onrole

Job summary

Lonza Oss is seeking a Senior Research Associate Biochemistry to advance ADS R&D in cytotoxic ADCs and related modalities. You will design, execute, document experiments, troubleshoot protocols, and optimize workflows using a full range of analytical techniques.

You will coordinate functional assays, prepare materials for stakeholders, and contribute to SOPs and ELN documentation in a dynamic, collaborative team at the Oss site.

Qualifications

• BSc/MSc in Biochemistry or Molecular Biology.
• 2–4 years relevant Biochemistry experience.
• Strong focus on lab work with high attention to detail and rigorous standards.
• Good verbal and written communication; team-oriented.
• Proficient in MS Office.

Responsibilities

• Plan and perform experiments; improve protocols as needed.
• Run enzymatic and chemical reactions on antibodies and proteins; troubleshoot.
• Purify proteins (Protein A chromatography, SEC, IEX) and analyze results.
• Conduct functional analyses (in vitro cytotoxicity, reporter assays, ELISA).
• Coordinate outsourced CRO assays and draft study protocols.
• Prepare materials for IP filings and internal/external presentations.
• Ensure timelines and quality of sub-projects; support meetings.
• Onboard new researchers and supervise interns.

Skills

MS Office

Laboratory skills

Attention to detail

Communication skills

Education

BSc/MSc in Biochemistry or Molecular Biology

Tools

SDS-PAGE

RP-UPLC

UPLC-MS

ELN

Job description

Senior Research Associate Biochemistry Location: Oss

A Senior Research Associate Biochemistry supports the ADS R&D agenda in the field of bioconjugation by contributing technical expertise and operational excellence. The Senior Research Associate independently plans, executes, and documents project‑specific activities, ensuring high scientific quality and reproducibility. They proactively troubleshoot experimental challenges, optimize workflows, and apply the full spectrum of analytical techniques available in the laboratory. In addition, the Senior Research Associate supports project management activities by preparing high‑quality materials for both internal and external stakeholders. Prime objective of the ADS-R&D Bioconjugates Research function (Oss) is to provide best-in-class targeted delivery technologies, i.e. development of protein conjugation technologies, linkers and payloads. General focus is on cytotoxic ADCs, however other modalities to be employed in indications such as immuno-oncology, targeted gene therapy, neuromuscular disease, neurodegeneration are also being pursued.

What you will get:

• An agile career and dynamic working culture.
• An inclusive and ethical workplace.
• Compensation programs that recognize high performance.
• A variety of benefits dependent on role and location. The full list of our global benefits can be found here: https://www.lonza.com/careers/benefits.
• The full-time annual base pay for this position in The Netherlands is expected to range between 48.000,- EUR and 67.200,- EUR. Initial salary placement within this range will be determined based on role‑related factors such as experience, qualifications, and expected contribution.

What you will do:

• Plans and performs experiments as described in protocols and improves upon these protocols. Is able to apply protocols beyond the original scope.
• Plans and executes enzymatic and chemical reactions on antibodies and other proteins and trouble‑shoots where appropriate.
• Performs various laboratory techniques for protein purification (protein A chromatography, SEC and IEX) and characterization (SDS-PAGE, RP‑UPLC, SE‑UPLC, UPLC‑MS) and critically assesses the results.
• Plans and executes functional analyses including cell-based assays (in vitro cytotoxicity, reporter cell lines) and ELISA-based assays and critically assesses the results.
• Coordinates biological assays outsourced to a CRO (e.g. communication with CRO, coordinating shipments and drafting study protocols).
• Collects experimental data, interprets the results, draws conclusions and proposes next steps to the supervisor.
• Prepares slides/presentations for internal and external use.
• Prepares and writes examples for IP filing.
• Is accountable for timelines and quality of sub‑projects within the bigger programs.
• Supports the preparations for internal group, project, and steering team meetings.
• Contributes to external collaborations and technical due‑diligences by preparing presentation slides that effectively communicate project progress and outcomes.
• Takes responsibility for small organizational projects, e.g. ordering laboratory equipment and improving on laboratory safety.
• Documents procedures, results and conclusions timely and accurately in Electronic Lab Notebooks (ELN).
• Review and approve ELN experiments from colleagues to guarantee accuracy and consistency.
• Prepares and revises standard operating procedures (SOPs).
• Oversees the inventory for antibodies, enzymes, small molecules and cell lines.
• In case analytical or preparative instruments malfunction, identifies issues and troubleshoots.
• Assists with onboarding of new research associates.
• Supervises interns.

What we are looking for:

• BSc/MSc degree in Biochemistry or Molecular biology.
• 2 - 4 years relevant experience in Biochemistry.
• Demonstrates a strong focus to laboratory work and a high attention to detail and strong experimental standards.
• Works closely with (senior) scientists, contributes to project progression, and communicates effectively within the team.
• Is able to interpret analytical data from experiments and converts these into next steps.
• Demonstrates problem solving and trouble shooting skills.
• Demonstrates good verbal and written communication and presenting skills.
• Acts as a reliable team member with a conscientious work ethic.
• Proficient in relevant software programs, including MS Office.

About Lonza

At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of. Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we value diversity and are committed to creating an inclusive environment for all employees. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board. Ready to shape the future of life sciences?