Senior Manager Local Study Operations

Amgen; Breda; On-site; EUR 110,000 - 170,000; Full time

Benefits offered by this job

On-site gym

Healthy restaurant

13th month

Health insurance

Job summary

Amgen Breda leads the labeling, assembly, storage and distribution of medicines and clinical research activities for multiple countries. The Senior Manager Local Study Operations will guide LSOMs, ensure timely, within-budget trials, and collaborate with global and local stakeholders to support Amgen’s clinical development strategy.

The role requires a clinical-operations background, ~7 years of leadership, and fluency in English and Dutch, with monthly presence in Breda.

Qualifications

• Degree educated with significant clinical operations experience.
• Around 7 years of leadership in clinical research settings.
• Experience delivering clinical trials in biotech, pharmaceutical, or CRO.
• Experience overseeing Netherlands clinical operations and regulatory requirements.
• Experience managing clinical research suppliers (CROs, labs, imaging).
• Strong knowledge of global clinical trial operations.
• Ability to manage resources, budgets, timelines and metrics.
• Excellent stakeholder management and cross-functional collaboration.
• Fluency in English and Dutch.
• Monthly presence in Breda office.

Responsibilities

• Lead and develop LSOMs to deliver country clinical trial portfolio.
• Oversee study execution, portfolio performance, resource planning, and quality.
• Collaborate with global and local stakeholders to support development strategy.
• Drive continuous improvement and adoption of best practices.
• Ensure studies are on time, within scope and budget.
• Monitor portfolio performance and address risks and quality trends.
• Manage LSOM and supplier performance to ensure high-quality execution.
• Plan resources and workloads across FTE and FSP teams.
• Align study strategy with Country‑Hub Head and cross-functional partners.

Skills

People leadership

Clinical operations

Clinical trials delivery

NL regulatory knowledge

Supplier management

Global trial ops

Resource budgeting

Timeline management

Stakeholder management

Cross-functional collaboration

Process improvement

English

Dutch

Office presence

Education

Degree educated

Job description

Career Category Clinical Job Description

If you feel like you’re part of something bigger, it’s because you are. At Amgen our shared mission—to serve patients—drives all that we do. It is key to becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.

Join us as: SENIOR MANAGER LOCAL STUDY OPERATIONS

At Amgen Breda medicines are labelled, assembled, stored and eventually shipped to various countries worldwide. Every day more than 1000 people with 42 different nationalities are working on supply chain processes, manufacturing, marketing and sales of our medicines and clinical research into new medicines.

LIVE

What you will do

In this vital role you will lead and develop a team of Local Study Operations Managers (LSOMs), ensuring the successful delivery of the country’s clinical trial portfolio from feasibility through study close‑out. You will drive operational excellence by overseeing study execution, portfolio performance, resource planning, and quality, while fostering collaboration across global and local stakeholders to support Amgen’s clinical development strategy. Lead, coach, and develop LSOMs, building a high‑performing team and strengthening capabilities to deliver increasingly complex clinical trials. Oversee the delivery of the country study portfolio, ensuring studies are executed on time, within scope and budget, and in line with quality and regulatory requirements. Monitor portfolio performance, identify risks and quality trends, and lead issue escalation, mitigation, and resolution. Manage LSOM and supplier performance, ensuring consistent, high‑quality study execution and achievement of portfolio objectives. Drive resource planning and workload allocation across FTE and FSP teams to optimize delivery and align with global priorities. Partner with the Country‑Hub Head and cross‑functional stakeholders to align study strategy, support study placement decisions, and ensure successful portfolio execution. Foster operational excellence through continuous improvement, knowledge sharing, adoption of best practices, and digital innovation.

WIN

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. What we seek in you as an experienced professional, are these qualifications and skills:

• Degree educated with significant clinical operations experience.
• Around 7 years of experience leading people, teams, projects, or programs within a clinical research environment.
• Proven experience delivering clinical trials within a biotech, pharmaceutical, or CRO setting.
• Experience managing clinical operations across the Netherlands, including strong understanding of local regulatory requirements around global clinical trials.
• Experience overseeing clinical research suppliers (e.g., CROs, central labs, imaging vendors).
• Strong understanding of global clinical trial operations and local regulatory requirements.
• Ability to manage resources, budgets, timelines, and performance metrics.
• Excellent stakeholder management, communication, and cross‑functional collaboration skills.
• Continuous improvement mindset with the ability to drive operational excellence and implement best practices.
• Fluency in English and in Dutch.
• Monthly presence in the Breda office.

THRIVE

What you can expect of us

As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well‑being. Therefore, Amgen is regularly recognized as a Best Place To Work. Vast opportunities to learn and move up and across our global organization. Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act. Generous Total Rewards Plan comprising competitive salary, bonus structure, fixed 13th month, holiday allowance and a collective health insurance. Focus on vitality with an on‑site gym, vitality program and a restaurant with healthy food.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics.

This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world’s leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

For more information, visit www.amgen.com and follow us on www.twitter.com/amgen