Senior Engineer, MES

Bristol-Myers Squibb; Leiden; On-site; EUR 110,000 - 140,000; Full time

Job summary

Bristol Myers Squibb Leiden is seeking an experienced MES Tech Lead (Recipe Authoring) to drive EBR recipe authoring, manage complex MES logic, and partner with MSAT and Manufacturing to ensure recipes reflect processes and quality expectations.

In this senior IC role you will own recipe design standards, review configurations, support validation (IQ/OQ/UAT), troubleshoot incidents, and guide cross-functional teams toward GMP compliance, data integrity, and robust change control.

Qualifications

• Bachelor’s degree in Engineering, Computer Science, Biotechnology, or related field.
• Hands-on MES recipe authoring experience in GMP environments.
• Expertise in EBR design, MES logic development, and recipe troubleshooting.
• Strong collaboration with MSAT, Quality, and Manufacturing.
• Strong analytical, troubleshooting, and documentation skills.

Responsibilities

• Lead MES recipe authoring and EBR workflow design.
• Define and maintain recipe design standards and best practices.
• Review and approve recipe designs, configurations, and changes.
• Support validation activities (IQ/OQ/UAT) related to recipes.
• Troubleshoot recipe logic and incidents; implement robust fixes.

Skills

MES recipe authoring

Emerson Syncade

GMP experience

MSAT collaboration

Troubleshooting

Education

Bachelor's degree in Engineering/CS/Biotechnology

Tools

MES integrations

Job description

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.Bristol Myers Squibb NetherlandsBristol Myers Squibb has been active in the Dutch market for over 50 years, employing people across a range of activities and business units in Utrecht, The Netherlands.The Netherlands is also home to our first European Cell Therapy facility, located at the Leiden Bio Science Park, the largest life sciences cluster of The Netherlands. This new state of the art facility is focused on commercial manufacturing with capabilities for multi-product Cell Therapy manufacturing. You can become part of this exciting journey. Check out this video if you want to know more about it!The Netherlands has everything it takes to become the medicines hub of Europe, the so-called Boston by the North Sea. As we continue to expand our footprint by building this new site, we are looking to grow our team.Would you like to become an important chain in our worldwide network to bring this new personalized treatment to patients suffering from blood cancer? Join us and be a game changer!For more information about Bristol Myers Squibb Netherlands, visit us at bms.com/nl or careers.bms.com/nlPosition SummaryThe MES Tech Lead (Recipe Authoring) is a senior technical individual contributor role with a primary focus on MES electronic batch record (EBR) recipe authoring and logic design in support of GMP Cell Therapy manufacturing operations. The role is responsible for the technical design, configuration, and lifecycle management of MES recipes, ensuring they accurately reflect manufacturing processes, Quality expectations, and MSAT intent.This position provides hands-on technical leadership in recipe authoring, complex MES logic, and configuration standards. It does not include people management responsibilities and instead focuses on deep technical expertise, solution ownership, and cross-functional collaboration.Duties/Responsibilities:Recipe Authoring & MES Logic OwnershipAct as the technical lead for MES recipe authoring, including EBR workflow design, parameterization, equipment interactions, and exception handling.Lead the design and implementation of complex, high-risk, or non-standard recipes in collaboration with MSAT and Manufacturing.Ensure accurate translation of process descriptions, batch records, and control strategies into MES recipe logic.Define and maintain recipe authoring standards, patterns, and best practices.Technical Review & GovernanceReview and provide technical approval for recipe designs, configurations, and changes developed by Recipe Authors.Ensure consistency, reusability, and compliance across all MES recipes.Support recipe versioning, change control, and migration activities across DEV/TEST/PROD environments.Quality, Compliance & ValidationEnsure all recipe authoring activities comply with GMP, data integrity principles, 21 CFR Part 11, and internal procedures.Provide technical input to validation strategies, risk assessments, and testing activities (IQ/OQ/UAT) related to recipes.Review validation documentation for recipe-related deliverables to ensure technical accuracy and audit readiness.Act as an MES recipe SME during deviations, investigations, CAPAs, and inspections.Incident Management & TroubleshootingServe as L3 technical escalation point for recipe-related MES issues impacting manufacturing.Perform advanced troubleshooting and root cause analysis of recipe logic and execution issues.Define and implement robust technical fixes to prevent recurrence of recipe-related incidents.Change & Release SupportPerform impact assessments for recipe changes, process updates, and MES enhancements.Ensure recipe change documentation meets Quality and compliance requirements.Support release execution activities in coordination with SysAdmins, Validation, and Automation teams.Cross-Functional CollaborationPartner closely with Manufacturing, MSAT, Quality, and Automation on recipe design and changes.Support tech transfers, new product introductions, and process changes from a recipe authoring perspective.Clearly communicate recipe design decisions, risks, and constraints to stakeholders.Continuous ImprovementIdentify opportunities to simplify recipes, reduce execution errors, and improve operator usability.Drive recipe standardization and harmonization across products and processes.Contribute to site and network forums related to MES recipe authoring and best practices.Required QualificationsBachelor’s degree in Engineering, Computer Science, Biotechnology, or a related technical or scientific field.Strong hands-on experience with MES recipe authoring (preferably Emerson Syncade) in a GMP-regulated manufacturing environment.Demonstrated expertise in EBR design, MES logic development, and recipe troubleshooting.Good understanding of manufacturing operations, MSAT collaboration, and Quality/GMP expectations.Strong analytical, troubleshooting, and documentation skills.Preferred QualificationsExperience in Cell Therapy, Biotech, or aseptic manufacturing environments.Experience with MES integrations and interfaces supporting recipe execution.Familiarity with validation methodologies and GxP documentation standards.Experience supporting audits and health authority inspections.Key CompetenciesDeep technical expertise in MES recipe authoringTechnical leadership without direct people managementStrong attention to detail and process understandingGMP compliance and data integrity mindsetStructured problem solving and root cause analysis Effective cross-functional communication#LI-OnsiteDisclaimer: For any third parties or external agencies, please, be informed we do not accept unsolicited requests, proposals, applications or profiles for any of our roles at BMS.Why You Should ApplyAround the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.How We WorkWhere you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.Supporting People with DisabilitiesBMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail] . Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.Candidate RightsBMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/Data ProtectionWe will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection .Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] with the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.R1605978 : Senior Engineer, MES