Senior Manager II, Manufacturing Operations, Cell Theraphy

Bristol-Myers Squibb; Leiden; On-site; EUR 110,000 - 165,000; Full time

Job summary

Bristol Myers Squibb Netherlands is seeking the Senior Manager II, Manufacturing Operations, Cell Therapy to lead end-to-end shift manufacturing performance. You will guide multiple teams, ensuring safe, compliant, and right-first-time execution while driving continuous improvement and CAPA across the cell therapy manufacturing process.

The role requires deep manufacturing experience in bioprocessing or related fields, strong leadership, and a commitment to safety, quality, and staff development

Qualifications

• Minimum of 10 years of relevant manufacturing, bioprocessing, protein biologics, or cell therapy manufacturing experience.
• Minimum of 6 to 8 years of leadership experience, including experience leading people leaders or managing multiple teams.
• Experience leading manufacturing operations in a dynamic, regulated, high-throughput environment is highly preferred.

Responsibilities

• Lead end-to-end shift manufacturing performance, including safety, quality, and schedule adherence.
• Drive continuous improvement, CAPA, and change control within cell therapy manufacturing.
• Coach and develop leaders to build leadership capability and improve team performance.
• Represent shift operations in leadership forums and ensure cross-functional alignment.

Skills

Leadership experience

Manufacturing operations

Cross-functional collaboration

Job description

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Bristol Myers Squibb Netherlands Bristol Myers Squibb has been active in the Dutch market for over 50 years, employing people across a range of activities and business units in Utrecht, The Netherlands. The Netherlands is also home to our first European Cell Therapy facility, located at the Leiden Bio Science Park, the largest life sciences cluster of The Netherlands. This new state of the art facility is focused on commercial manufacturing with capabilities for multi-product Cell Therapy manufacturing. You can become part of this exciting journey. Check out this video if you want to know more about it! The Netherlands has everything it takes to become the medicines hub of Europe, the so-called Boston by the North Sea. As we continue to expand our footprint by building this new site, we are looking to grow our team. Would you like to become an important chain in our worldwide network to bring this new personalized treatment to patients suffering from blood cancer? Join us and be a game changer! For more information about Bristol Myers Squibb Netherlands, visit us at bms.com/nl or careers.bms.com/nl

Position Summary Senior Manager II, Manufacturing Operations, Cell Therapy is head of ERT and a member of the Manufacturing Leadership Team and accountable for leading E2E full-shift manufacturing performance.

This role is a people leader of people leaders/individuals and provides leadership across multiple manufacturing teams and unit operations to ensure safe, compliant, right-first-time execution of the cell therapy manufacturing process.

The Manufacturing Leadership Team is working together to ensure safe, compliant, reliable, and high-performing manufacturing operations. The Senior Manager II combines direct operational accountability for shift performance with broader leadership responsibilities across quality, safety, training, people development, continuous improvement, schedule adherence, and issue escalation.

Manufacturing Leadership Team Accountability

• Contributes to Manufacturing strategy, priorities, site performance goals, and leadership routines as a member of the Manufacturing Leadership Team.
• Represents shift performance, risks, resource needs, improvement opportunities, and escalation topics in Manufacturing Leadership Team forums.
• Partners with Associate Directors and peer Senior Manager’s to align standards, priorities, escalation practices, and performance expectations across Manufacturing.
• Ensures consistent execution of manufacturing standards across shifts and manufacturing teams while enabling timely resolution of cross-shift and cross-functional issues.

Values and Leadership

• Leads by example and drives leaders and teams to adhere to BMS values.
• Creates an engaging, accountable, inclusive, and learning culture across the shift.
• Coaches and develop people leaders and/or individual contributors to build leadership capability, strengthen decision making, and improve team performance.

Quality

• Accountable for compliant execution of manufacturing shift operations within master production schedule, scope, quality, and budget.
• Maintains an audit-ready manufacturing environment and supports inspection readiness activities.
• Driving right-first-time performance, reduces deviations, eliminates repeat causes, and ensures meaningful CAPA and change control implementation.
• Represents shift operations in manufacturing tier meetings, quality forums, and review boards as required.

Safety

• Fosters an effective safety culture across the shift and ensures compliance with EOHSS standards and site safety expectations.
• Ensures manufacturing leaders identify, assess, elevate, and mitigate safety and compliance risks.
• Participates in safety Gemba walks, emergency response activities, event triage, and operational risk reviews as required.

Shift Performance

• Accountable for the overall performance of an entire manufacturing shift, including safety, quality, delivery, cost, people, compliance, and schedule adherence.
• Serves as the shift escalation point for major operational issues, staffing constraints, technical challenges, and manufacturing events.
• Ensures clear prioritization, communication, and handover between shifts and across support functions.
• Uses KPIs, tier processes, and metric control plans to monitor performance, identify trends, and drive timely corrective actions.

Continuous Improvement and Operational Excellence

• Identifies and implements improvements that contribute to site and department goals while maintaining validated and compliant processes.
• Deploys lean principles to improve shift efficiency, reduce waste, remove roadblocks, and strengthen operational discipline.
• Leads or participates in complex operational projects, process improvements, and cross-functional initiatives.

Training and People Development

• Accountable for shift training compliance and readiness, including ensuring leaders understand and act on training gaps.
• Accountable for onboarding, qualification, and technical capability building for manufacturing staff.

Qualifications

• Minimum of 10 years of relevant manufacturing, bioprocessing, protein biologics, or cell therapy manufacturing experience.
• Minimum of 6 to 8 years of leadership experience, including experience leading people leaders or managing multiple teams.
• Experience leading manufacturing operations in a dynamic, regulated, high-throughput environment is highly preferred.

Why You Should Apply

We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

R1606312 : Senior Manager II, Manufacturing Operations, Cell Theraphy Data Privacy Link

We’re creating innovative medicines for patients fighting serious diseases. We’re also nurturing our own diverse team with inspiring work and challenging career options. No matter the role, each one of us makes a contribution. And that makes all the difference.