Scientist Lipid Nanoparticle Gene Therapy

Sanquin; Amsterdam; On-site; EUR 45,000 - 55,000; Full time

Benefits offered by this job

8.33% end-of-year bonus

Travel cost reimbursement

PFZW pension plan

201 hours annual leave

Job summary

Sanquin in Amsterdam invites applications for a postdoctoral position focused on lipid nanoparticle mediated gene delivery to hematopoietic stem cells. This translational program aims to establish non-viral in vivo targeting and gene-editing approaches in a collaborative, international environment.

The two-year, full-time appointment includes CAO Sanquin compensation, an 8.33% end-of-year bonus, partial travel-cost reimbursement, a PFZW pension plan, and 201 hours of annual leave.

Qualifications

• Postdoc with experience in nanoparticle mediated gene delivery and gene editing.
• Experience applying these approaches to hematopoietic stem cells or related tissues.
• Ability to work in an international research setting and collaborate across teams.

Responsibilities

• Conduct experimental studies on lipid nanoparticle mediated gene delivery to hematopoietic stem cells and other cell types.
• Contribute to study design, data interpretation, and publication of results.
• Collaborate within the Division of Research and Lab Services on translational aspects of the program.

Skills

Nanoparticle mediated gene delivery

Gene editing

Hematopoietic stem cells

Education

PhD in molecular biology or related field

Job description

Gene therapy program Sanquin. The gene therapy group within Sanquin focuses on further improvement of the quality of life of patients with hematological disorder. Within our program we have an opening for an expert on lipid nanoparticle mediated gene delivery to hematopoietic stem cells and other cells and tissues. In this novel line of research we aim to establish non-viral approaches for in vivo targeting of hematopoietic stem cells. For this program we are looking for a postdoc with experience in nanoparticle mediated gene delivery as well as gene‑editing.

Division of Research and Lab Services The Division of Research and Lab Services of Sanquin is home to 250 researchers, including over 60 PhD students and 30 postdocs. Research at Sanquin is organized in four strategic themes: Anemia, Bleeding & Hemostasis, Immunity & Inflammation, and Immune Therapy. The joint mission of research at Sanquin is to develop novel methods and approaches using blood cells and blood products to prevent, diagnose, treat, or cure disease in donors and patients. Research activities cover the full spectrum of early inventions, development into novel products and services, donor studies, and clinical studies in patients. Our research labs are equipped with state‑of‑the‑art facilities, including flow cytometry and cell sorting, macromolecular mass spectrometry and proteomics, and imaging. Many of our scientists have academic affiliations with Dutch Universities and University Medical Centres. Sanquin is strategically located in Amsterdam, with a special tie to the Amsterdam UMC (Joint Landsteiner Laboratory).

Our expectations

We anticipate the newly recruited postdoc to contribute with her/his unique expertise, complementing our existing research portfolio. This includes genetic and cellular approaches to correct and cure hematological disorders.

Our offer

We offer an international – academically oriented – research environment with state‑of‑the‑art equipment. The position will be for 2 years.

• A challenging translational project in a multi‑disciplinary and enthusiastic international team
• Salary and conditions are conform CAO Sanquin
• 8.33% end‑of‑year bonus; i.e. a thirteenth month in case of full‑year employment
• Partial reimbursement of travel costs
• Pension plan with Pensioenfonds Zorg & Welzijn (PFZW)
• At full‑time employment (36 hours) 201 hours of leave per annum

Applications

If you are interested in this position, please apply by submitting your extended CV before August 31, 2026. More information can be obtained from the website sanquin.org/research/research-vacancies or by sending an email to the Prof. dr. Jan Voorberg ([e-mail]) or Dr. Despoina Trasanidou ([e-mail]).

Acquisition is not appreciated. Sanquin does not accept unsolicited help from agencies for vacancies. CVs sent (in any form whatsoever) by placement agencies to any Sanquin employee without a valid written assignment by HR Sanquin will be considered property of Sanquin for which no compensation is owed in any way.