Experienced Scientist Biotherapeutics RD

8852-Janssen Vaccines & Prevention B.V. Legal Entity; Netherlands; On-site; EUR 54,000 - 85,000; Full time

Benefits offered by this job

Annual bonus

Vacation days and parental leave

Bereavement leave

Well-being programs

Insurance plans

Job summary

Johnson & Johnson Leiden site is seeking a Scientist to develop, optimize, and scale-up Lipid Nanoparticle (LNP) drug product processes from early to late-stage development. This role blends hands-on lab work with cross-functional collaboration to ensure robust, scalable, and GMP-ready processes.

The candidate will design and execute development studies, analyze data, support technology transfer, and work with Analytical Development, MSAT, Quality, Manufacturing and Regulatory teams to drive

Qualifications

• MSc or PhD in Pharmaceutical Sciences, Chemical Engineering, Biochemistry, or related field.
• Experience in process development and/or LNP formulation development.
• Hands-on laboratory experience in drug product or nanoparticle development.

Responsibilities

• Design and execute LNP process development studies across early and late development stages.
• Perform hands-on laboratory work including process design, optimization, and characterization.
• Analyze and interpret data to support process understanding, optimization, and decision-making.
• Support process characterization activities, including identification of CPPs and development of robust processes.
• Contribute to scale-up and manufacturing readiness, including support of technology transfer to internal sites or CMOs.
• Collaborate across Analytical Development, MSAT, Quality, Manufacturing, and Regulatory teams to align on process strategy.
• Document experimental work and results in accordance with GMP and data integrity requirements.
• Participate in troubleshooting activities and continuous process improvement initiatives.

Skills

Scientific problem-solving

Cross-functional collaboration

Data interpretation

Written & verbal communication

Project multitasking

Education

MSc/PhD in Pharmaceutical Sciences or related field

Tools

LNP formulation

Process scale-up

GMP principles

Job description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Discovery & Pre-Clinical/Clinical Development

Job Sub Function

Biotherapeutics R&D

Job Category

Scientific/Technology

All Job Posting Locations

Leiden, South Holland, Netherlands

Job Summary

The Scientist will support the development, optimization, and scale-up of Lipid Nanoparticle (LNP) drug product processes from early to late-stage development. The role combines hands-on laboratory work with strong cross-functional collaboration to ensure robust, scalable, and GMP-ready processes.

Key Responsibilities

• Design and execute LNP process development studies across early and late development stages
• Perform hands-on laboratory work including process design, optimization, and characterization
• Analyze and interpret data to support process understanding, optimization, and decision-making
• Support process characterization activities, including identification of CPPs and development of robust processes
• Contribute to scale-up and manufacturing readiness, including support of technology transfer to internal sites or CMOs
• Collaborate cross-functionally with Analytical Development, MSAT, Quality, Manufacturing, and Regulatory teams to ensure alignment on process strategy and execution
• Document experimental work and results in accordance with GMP and data integrity requirements
• Participate in troubleshooting activities and continuous process improvement initiatives

Qualifications

• MSc or PhD in Pharmaceutical Sciences, Chemical Engineering, Biochemistry, or related field
• Relevant experience in process development and/or LNP formulation development
• Strong hands-on laboratory experience in drug product or nanoparticle development
• Understanding of process scale-up, technology transfer, and GMP principles

Required Skills & Competencies

• Strong scientific problem-solving and data interpretation skills
• Hands-on, proactive, and detail-oriented approach
• Ability to work effectively in a cross-functional, matrixed environment
• Clear and concise communication skills (written and verbal)
• Ability to manage multiple priorities in a dynamic development environment

Preferred Qualifications

• Experience with mRNA/LNP platforms or advanced therapies
• Familiarity with process validation (e.g., LCPV) and manufacturing support
• Exposure to late-stage development or commercial readiness activities

Job role is fixed for one year with possibility to extend #DPDS

Required Skills: Preferred Skills:

• Analytical Reasoning
• Biochemistry
• Chemistry
• Manufacturing and Control (CMC)
• Coaching
• Collaboration
• Conducting Experiments
• Data Quality
• Drug Discovery Development
• Molecular Diagnostics
• Patent Applications
• Pharmacogenetics
• Report Writing
• Research Documents
• Scientific Research
• Technologically Savvy
• Written Expression

Anticipated base pay range

The anticipated base pay range for this position is: €53,500.00 - €85,445.00

Benefits

• an annual bonus with set target (% of pay) depending on pay grade / location, where the actual amount is based on the employees’ and companies’ performance of the previous calendar year, or sales commissions.
• Moreover, we offer vacation days, parental leave for a minimum of 12 weeks, bereavement leave, caregiver leave, volunteer leave, well-being reimbursement, programs for financial, physical and mental health.
• We also offer service anniversary and recognition awards, and subject to the terms of their respective plans, employees - and in some location’s eligible dependents - can participate in several insurance plans.
• For more information, visit Employee benefits | Supporting well-being & career growth | Johnson & Johnson Careers.
• *This is for informative purposes only. Amounts and actual benefits may vary by location and are subject to change.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.

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