Postdoc: Covalent Inhibitor Chemist for Cancer (Hybrid)

Leiden University; Leiden; Hybrid; EUR 41,000 - 64,000; Full time

Benefits offered by this job

6-month contract

High salary (€3706-€5760)

ABP pension

Transport reimbursement

Flexible hours

Hybrid work possible

Home internet allowance

Job summary

Leiden University is seeking a postdoctoral synthetic/medicinal chemist to design, synthesize and optimize covalent small molecules targeting cancer pathways. The role involves chemoproteomics, selectivity assessment, and preliminary functional testing in cell-based assays within a collaborative team at Leiden Bioscience Park.

You will join the Leiden Institute of Chemistry under supervisor Madeline E. Kavanagh.

Qualifications

• Essential: Proficient synthetic/medicinal chemist with ability to design and troubleshoot synthetic routes.
• Preferred: Experience in small molecule drug development, SAR studies, property optimization.
• Optional: Functional characterization of inhibitors in cell-based/biochemical/biophysical assays.

Responsibilities

• Design, synthesis and characterization of covalent small molecules.
• Research reporting in group/department meetings, conferences and publications.
• Team work/supervision – integrate with existing lab members and support biological studies.

Skills

Synthetic chemistry

Enantioselective synthesis

Covalent chemistry

Drug development experience

Education

PhD in chemistry

Tools

NMR

LC-MS

Job description

Leiden University is seeking a postdoctoral synthetic/medicinal chemist to design, synthesize and optimize covalent small molecules targeting cancer pathways. The role involves chemoproteomics, selectivity assessment, and preliminary functional testing in cell-based assays within a collaborative team at Leiden Bioscience Park.

You will join the Leiden Institute of Chemistry under supervisor Madeline E. Kavanagh.