PhD in Metabolic footprint in human enterovirus infections along gut-brain axis

Amsterdam UMC; Amsterdam; On-site; EUR 36,000 - 45,000; Full time

Benefits offered by this job

8.3% end-of-year bonus

Public transport reimbursement

Bike scheme

Secondments to JLU Giessen and Medical

University Innsbruck

Job summary

Amsterdam UMC in Amsterdam invites applications for a four-year research contract (36 hours/week) to study metabolic changes during enterovirus infections in gut and brain organoids, with comparisons of immunocompetent and immunodeficient models. Planned secondments to Giessen (Germany) and Innsbruck (Austria) will accompany comprehensive omics analyses and pathway modelling.

You will be trained in hazard identification and biosafety, with a tailor-made pre-MBA programme and ongoing professional

Qualifications

• Master's degree in biomedical sciences, infection, immunity or related fields.
• Experience working with viruses, mammalian cell culture, qPCR, and bioinformatics preferred.
• Excellent oral and written communication skills in English (C1/C2 CEFR).
• Mobility: not resided/worked in the Netherlands for more than 12 months in the 36 months before 1 April 2027.

Skills

Bioinformatics

English proficiency

Education

Master's degree in Biomedical Sciences

Tools

qPCR

Mammalian cell culture

Job description

to study metabolic changes during infection with enteroviruses belonging to species B and C in gut and brain organoids; to study differences in host responses between immunocompetent and immunodeficient patient gut organoids; to perform integrative omics and genome-scale metabolic modelling for EV-B and EV-C infected organoids. Master's degree in biomedical sciences, infection, immunity or related fields; experience working with viruses, mammalian cell culture, qPCR, and bioinformatics are preferred; excellent oral and written communication skills in English (minimum C1/C2 CEFR level); an interest in working in a multidisciplinary research group; have not resided/carried out work or studies in the Netherlands for more than 12 months in the 36 months immediately before 1 April 2027 (transnational mobility rule). A contract with Amsterdam UMC for 36 hours per week for 4 years (probation of 6 months). The opportunity to work on large-scale and in-house research with motivated colleagues from all over the world. Planned secondments in the Justus Liebig University Giessen (Germany) and the Medical University Innsbruck (Austria), Training in safety and biosecurity aligned with international best practices. You will be trained in hazard identification, containment, incident reporting, and dual-use/gain-of-function issues. An opportunity to take part in a tailor-made pre-MBA programme to develop entrepreneurial and commercial skills and other network-wide training opportunities including conferences and courses, a Personal Development Plan, non-academic coaching, and workshops on topics including ethics and sustainability and AI/LLM.

Classification in salary scale OIO: € 3,217 to € 4,077 gross for full-time employment (depending on experience). In addition to a good basic salary, we offer 8.3% end-of-year bonus. Calculate your net salary here.

• 100% reimbursement for public transport travel costs
• €0.18 per km up to a maximum of 40 km each for private transport
• Take advantage of our good bike scheme.

Do you prefer walking or cycling?