Manufacturing Operator/Technician (Immunology, BioTech)

MAT Research; Leiden; On-site; EUR 50,000 - 70,000; Full time

Benefits offered by this job

25 vacation days

Competitive base salary

Job summary

A biotech company in the Netherlands seeks a Manufacturing Operator/Technician in Leiden. The candidate will drive the production and quality control of MAT diagnostic kits, ensuring compliance with GMP and maintaining high documentation quality. Ideal applicants have a background in biotech manufacturing, especially in immunology, and at least three years of relevant experience. A competitive salary and benefits, including vacation days, are offered, alongside potential business trips.

Qualifications

• At least 3 years of experience in biotech or pharmaceutical manufacturing.
• Experience with PBMC isolations and cellular assays.
• Familiarity with GMP and ISO:9001 regulations.

Responsibilities

• Execute end-to-end manufacturing processes for MAT kits.
• Follow SOPs and ensure compliance with GMP.
• Conduct in-process quality control tests for product reliability.

Skills

Biotech manufacturing

Problem-solving

Attention to detail

Technical writing

Inventory management

Education

Bachelor’s or Master’s degree in biological/medical sciences

Tools

ELISA

Flow Cytometry

GMP compliance tools

Job description

MAT Research is a pioneering company in the field of pyrogen testing, committed to ushering in a new era of ethical and accurate diagnostics. Since 2016, we have been leading the development of the Monocyte Activation Test (MAT), an animal‑free alternative to traditional Rabbit Pyrogen Tests. Our ready‑to‑use MAT kits offer a robust and highly reliable method for detecting a broad range of pyrogens in parenteral drugs. ISO:9001:2015 certified, we uphold the highest standards of quality in all our products and services. By focusing on in‑vitro human‑based testing, we aim to drastically increase patient safety while saving hundreds of thousands of animal lives each year. We are steadfast supporters of the European Pharmacopoeia's vision to replace animal‑based tests with MAT by 2026. For more details, go to our job page.

As we continue to scale, we are looking for a Manufacturing Operator/Technician to join our growing team in Leiden, Netherlands. You will play a vital role in the production, quality assurance, and scale‑up of our MAT diagnostic kits. This role is ideal for professionals with a biotech manufacturing background, particularly in immunology‑focused production environments.

Your key responsibilities will include:

• Manufacturing & Production
• Equipment & Process Maintenance
• Quality Control & Compliance
• Material & Inventory Management
• Process Improvement & Reporting

To fulfill these responsibilities, you will:

• Execute end‑to‑end manufacturing processes, including preparation, formulation, and packaging of MAT kits.
• Follow Standard Operating Procedures (SOPs), batch records, and Good Manufacturing Practices (GMP) to ensure consistency and quality.
• Assist in the scale‑up of manufacturing processes, optimising workflow efficiency.
• Operate and maintain bioprocessing and immunoassay equipment.
• Perform routine calibration, sterilisation, and maintenance of manufacturing tools.
• Monitor and troubleshoot production deviations or process inefficiencies.
• Conduct in‑process quality control tests to ensure product reliability.
• Work closely with Quality Assurance (QA) teams to maintain compliance with ISO:9001:2015, GMP, and regulatory requirements.
• Maintain accurate batch records and production documentation to ensure traceability.
• Prepare, measure, and handle biological materials, PBMCs, reagents, and consumables.
• Ensure proper storage conditions and inventory tracking for raw materials and finished products.
• Support continuous improvement initiatives to optimise production workflows.
• Assist in developing new SOPs, technical documentation, and training materials.
• Report deviations and contribute to troubleshooting investigations and corrective actions.

Additional requirements:

• Living near Leiden or able to relocate without support.
• Bachelor’s (HLO/HBO) or Master’s (University) degree in biological/medical sciences or equivalent, preferably with a strong immunology/cellular background.
• Additional certifications in bioprocessing, GMP, or quality control are a plus.
• At least 3 years of hands‑on experience in biotech, pharmaceutical, or immunology‑based manufacturing, PBMC isolations, cellular assays, and analytical‑based assays (ELISA, Flow Cytometry) according to regulatory standards such as ICH is a pre.
• Familiarity with GMP, ISO:9001, and regulatory compliance for biotech production.
• Strong attention to detail with excellent documentation and data recording skills.
• Ability to work in a cleanroom or controlled laboratory environment.
• Problem‑solving mindset with the ability to troubleshoot and improve processes.
• Comfortable with inventory and logistics software, capable of managing resources efficiently.
• Excellent skills in technical writing and reporting.
• Fluent in English; proficiency in Dutch, German, or French is a major plus.
• Willing to hit the road for occasional business trips.

Your compensation will be:

• Competitive base salary (Full‑time 40 h/week)
• 25 vacation days + national holidays