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A leading academic institution is seeking a researcher with a PhD in Biomedical Sciences or Neuroscience to study neurodegeneration using iPSC models. Responsibilities include managing research programs, supervising experiments, and engaging in teaching. Candidates should possess strong communication skills and a robust publication record in molecular neuroscience. This role offers a dynamic research environment contributing to groundbreaking studies.
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The focus of Professor Patani’s lab is understanding the molecular and cellular mechanisms underpinning neurodegeneration. The lab uses a variety of patient-derived iPSC lines to investigate disease-related events at the molecular level across different relevant cell types, including motor neurons, astrocytes, and microglia.
The post holder will join an established and dedicated team of researchers using human induced pluripotent stem cells to study fundamental cellular and molecular mechanisms of neurodegeneration. The primary activity will be to resolve the molecular basis of neuronal degeneration and glial dysfunction, with a particular focus on aberrant RNA metabolism, especially post-transcriptional mechanisms of disease. The role involves utilizing state-of-the-art molecular methods combined with cutting-edge sequencing approaches to explore the complex interactions between aberrant splicing and cellular homeostasis. This is a compelling opportunity to contribute to ground-breaking, high-impact research within a globally diverse scientific community.
PhD in Biomedical Sciences, Neuroscience, or relevant field.
Extensive knowledge of neurodegeneration.
Experience with iPSC differentiation and mouse models.
Phenotyping iPSC-derived cells.
Advanced molecular biology skills.
Experience with RNAseq and high-throughput imaging data.
Handling human post-mortem tissue.
Computer coding skills.
Supervisory experience.
Strong publication record and recognition in molecular neuroscience.
Self-organized with good prioritization skills.
Excellent communication skills.
Proactive problem-solving and initiative.
Interest in supervising young researchers.
Commitment to high-quality research.
Interpersonal skills for multidisciplinary collaboration and learning new skills.