Senior Principal Scientist, IMCB

A*STAR RESEARCH ENTITIES; Pasir Panjang; On-site; MYR 250,000 - 300,000; Full time

Job summary

A research institution in Negeri Sembilan is seeking an experienced researcher to lead a project in vascular biology, focusing on iPSC-based modeling. Candidates should hold a PhD/MD-PhD and have significant postdoctoral experience, along with a proven record in securing research funding. The role involves mentoring a team and developing innovative research platforms.

Qualifications

• At least 8–10 years of postdoctoral and/or independent PI experience in stem cell biology.
• Internationally recognised track record of high-impact publications.
• Strong commitment to collaborative, interdisciplinary research.

Responsibilities

• Lead an independent research programme in iPSC-based modeling of vascular biology.
• Develop novel stem cell-derived platforms for studying human vascular systems.
• Supervise and mentor a research team, including students and postdoctoral fellows.

Skills

Research funding

Team leadership

Collaborative research

Education

PhD or MD/PhD in Biomedical Sciences, Cell Biology, Developmental Biology

Job description

Key Responsibilities

• Lead an independent research programme in iPSC-based modeling of vascular biology, including endothelial cell development, vascular dysfunction, and vascular contributions to complex diseases
• Develop novel stem cell-derived platforms for studying human vascular systems and their interactions with other cell types or organs (e.g. brain, liver, tumor microenvironment)
• Translate disease models into platforms for target discovery, therapeutic screening, or biomarker identification
• Secure external research funding from national and international sources
• Supervise and mentor a research team, including students and postdoctoral fellows
• Build collaborative links with partners across A*STAR, academia, hospitals, and industry

Qualifications and Requirements

• PhD or MD/PhD in Biomedical Sciences, Cell Biology, Developmental Biology, or a related field
• At least 8–10 years of postdoctoral and/or independent PI experience in stem cell biology, vascular biology, or regenerative medicine
• Internationally recognised track record of high-impact publications and scientific leadership
• Proven success in securing competitive research funding and building productive research teams
• Strong commitment to collaborative, interdisciplinary research and mentoring