Senior Research Scientist - Cell Biology & Tissue Models

Pandorum Technologies Pvt. Ltd.; Bengaluru; On-site; INR 900,000 - 1,500,000; Full time

Job summary

Pandorum Technologies Pvt. Ltd. is seeking a hands-on Senior Research Scientist to lead the development of cell-based assays and 3D tissue models within the Cellular Engineering team. The role involves mammalian cell culture, disease-relevant model development and analysis of biological activity.

The candidate will design controlled experiments, establish human 3D cultures such as spheroids or organoids, and mentor junior team members while maintaining rigorous records and SOPs.

Qualifications

• PhD in biotechnology, cell biology or a related life-science discipline.
• Hands-on experience with mammalian cell culture and 3D tissue models.
• Independent project design and ability to mentor junior team members.

Responsibilities

• Perform biochemical, molecular and cell-based assays; document results.
• Design controlled experiments with predefined objectives and replication.
• Establish human cellular, multicellular and 3D tissue models (spheroids/organoids).
• Develop assays for biological activity in disease-relevant systems.
• Characterize materials with biochemical and molecular methods; perform quantitative assays.
• Evaluate responses, model reproducibility and tissue-relevant function with controls.
• Collaborate to improve assay variability and method reproducibility.
• Prepare technical reports, present findings and contribute to study documentation.
• Own experimental plans, maintain SOPs and mentor staff.

Skills

Mammalian cell culture

3D tissue models

Quantitative imaging

Molecular biology

Education

PhD in Biotechnology or related life-science discipline

Job description

Senior Research Scientist - Cell Biology & Tissue Models

3 - 6 years

Full-Time

Role Overview

We are seeking a hands-on Senior Research Scientist to lead the development and application of cell-based assays and three-dimensional tissue models within Pandorum’s Cellular Engineering team. The position combines mammalian cell culture, disease-relevant model development, biochemical analysis and evaluation of biological activity.

Required Qualifications

• Ph.D. in Biotechnology, Cell Biology, Molecular Biology, Biochemistry, Bioengineering, Regenerative Medicine, Stem Cell Biology, Pharmacology, Neuroscience or a related life-science discipline.

Experience: Typically 3–6 years of relevant post-Ph.D. research or industry experience; demonstrated scientific independence and directly relevant expertise will guide assessment.

Key Responsibilities

• Perform biochemical, molecular and cell-based assays; analyze results and maintain complete laboratory records.


• Design controlled experiments with predefined objectives, appropriate comparators and biological replication; retain complete records and critically assess all findings.


• Establish, maintain and characterize human cellular, multicellular and 3D tissue models, including spheroids or organoids appropriate to the research question.


• Develop and qualify assays for biological activity in disease-relevant systems, drawing on expertise in inflammation, fibrosis and tissue repair.


• Characterize experimental materials using appropriate biochemical and molecular methods, and perform quantitative cell-based assays.


• Evaluate concentration-dependent and time-dependent responses, model reproducibility and tissue-relevant function alongside viability and appropriate controls.


• Work with colleagues to investigate assay variability, establish suitable controls and improve method reproducibility.


• Prepare technical reports, present findings and contribute to assay transfer and preclinical study documentation.


• Own experimental plans and milestones, maintain SOPs and technical reports, communicate findings clearly and mentor junior team members.

Preferred Experience

• Experience with quantitative imaging, molecular assays and integration of structural and functional readouts; assay transfer or collaboration with external research laboratories.


• Strong hands-on mammalian cell-culture, cell-biology and molecular-biology skills, with evidence of independent experimental design, troubleshooting and quantitative data interpretation.


• Ability to perform and interpret biochemical or molecular characterization alongside quantitative cell-based assays, with clear documentation and scientific communication.


• Demonstrated independent ownership of disease-relevant assay development, including hands‑on establishment and characterization of at least one human 3D culture, spheroid, organoid or multicellular tissue model.


• Scientific depth in inflammation, fibrosis, tissue repair, neurobiology or a related area, with the ability to apply that expertise across experimental systems.


• Working understanding of cellular signaling, gene expression and molecular mechanisms relevant to cell-based research.


• Experience with organoid development, stem‑cell differentiation or advanced human co‑culture models.


• Experience with induced pluripotent stem cell (iPSC) maintenance and characterization, directed differentiation, or neuronal/glial cultures.


• Experience with extracellular‑vesicle (EV) biology, biochemical characterization or functional and potency assays.

Required Skills

3D tissue models 3D Cell culture EV biology iPSC characterization biochemical characterization 3D spheroid Organoid culture