Senior Research Associate

Cadila Pharmaceuticals Limited; Dholka; On-site; INR 600,000 - 900,000; Full time

Job summary

Cadila Pharmaceuticals Limited seeks a lab-scale development specialist to demonstrate and scale up DMF/NDMF molecules in the lab, conducting process optimization before scaling to production. You will study unit operations such as crystallization, distillation, drying, and extraction, and perform kinetic observations and engineering calculations during scale-up.

The role involves ensuring documentation, archiving, and safe, compliant lab practices while coordinating with R&D, TT, EHS, and

Qualifications

• Experience in lab scale-up and tech transfer workflows.
• Strong understanding of unit operations and process optimization.
• Familiarity with crystallization, distillation, drying and extraction processes.

Responsibilities

• Demonstrate and scale up DMF/NDMF molecules in lab settings.
• Coordinate process param studies and optimization before scale-up.
• Troubleshoot plant-level issues and perform root-cause analysis.

Skills

Kilo Lab operations

Technology transfer

Process optimization

Scale-up chemistry

Root cause analysis

Dynochem analysis

Tools

Dynochem

XRD

PSD

Multimill

Job description

Job Description:

• Responsibility Lab demonstration & scale up of new DMF and NDMF molecules, Process Optimization before Scale-up activities, Execution of Kilo Lab batches & technology transfer activity.
• Principal Tasks and Responsibilities: Understanding the process in details with concerned scientist with experiments in the lab.
• Suggest/Discuss problem that may arise at plant level prospect.
• Study the operational parameters of different unit operations like crystallization, distillation, drying, and extraction and optimize those parameters based on energy basis, cost basis, safety concerns accordingly.
• Preparing list of facility requirement like equipment, utilities at Production.
• To find out the root cause of the failed batches in plant and take up experiments based on the proposed solution.
• Solvent recovery and system capacity enhancement.
• Scale up of products from R&D to plant scale by doing engineering calculations and observing the kinetics involved in the reaction.
• Responsible for all documents / records maintained properly.
• Ensure old records are archived properly and are retrievable.
• To maintain quality and safety standards in Lab and Kilo lab.
• Prepare trend analysis of various tests, trials & experiments in order to arrive at logical conclusions by using dynochem.
• Co-ordinate with Maintenance regarding breakdown and preventive maintenance of equipment’s or facility.
• Coordination with R&D, TT, ARL, EHS, Engineering Dept. and Plant for smooth functioning of Lab & Technology Transfer activities.
• PSD related batches/experiments plan in Air Jet mill/Multimill.
• Crystallization and polymorphic studies.
• XRD and PSD analysis and handling of instruments.

Requirements: