Scientist - UPD (Mammalian)- Biosimilar

Enzene Biosciences Ltd.; Pune District; On-site; INR 1,500,000 - 2,800,000; Full time

Job summary

Enzene Biosciences Ltd. is seeking an experienced Upstream (Mammalian) specialist with 8–11 years of hands-on work in mammalian cell culture. The role involves designing media/feed strategies, executing fed-batch and perfusion processes, and supervising daily operations to ensure experimental rigor.

Collaboration across R&D and manufacturing is essential to drive process development. The candidate should have strong aseptic technique experience, proficiency with tools like

Qualifications

• 1. 8 to 11 years of experience with M.Tech/M.Sc. degree in biotechnology/ Biochemical Engineering, Biochemistry, Biology or a related scientific discipline.
• 2. Ability to work and collaborate in cross functional teams, research, development, manufacturing in a fast pace and dynamic team setting.

Responsibilities

• Design and execute media/feed screenings and optimizations using ambr250 and bioreactor culture.
• Develop, including fed batch and perfusion cell culture processes.
• Plan, assign, and supervise daily operations to ensure proper experiment execution.
• Experience with aseptic techniques and cell culture in lab-scale formats.
• Handle mammalian cell culture using bench top and single-use bioreactors; high throughput systems.

Skills

Interpersonal skills

Verbal communication

Written communication

Problem solving

Team player

Education

M.Tech/M.Sc. in biotechnology or Biochemical Engineering

Biochemistry/Biology or related

Tools

Cedex

ViCell

Osmometer

Job description

Role& responsibilities - Upstream(Mammalian)

• Design and execute media/feed screenings and optimizations using ambr250and bioreactor culture
• development, including fed batch and perfusion cell culture processes.
• Planning, assigning, and supervising daily operations to ensure properexperiment execution
• Experience with aseptic techniques, cell culture in various lab-scaleformats, small to medium scale
• bioreactors, and cell counting methods and equipments like Cedex, ViCell, Osmometer
• Handling of Mammalian cell culture using bench top, single use bioreactorand high throughput
• systems such as ambr250, WAVE bioreactors and ATF systems.
• Excellence in cell culture process development by Fed batch as well asPerfusion process.
• Bioreactor culture development including fed-batch, N-stage perfusiontechnologies (2 to 50L scale)
• with both glass and single-use cell culture technologies
• Daily review of ongoing experimental data
• Reviewing functional PDR, TTD etc.
• Good interpersonal, verbal and written communication skills.
• Excellent communication and presentation skills and aptitude for problemsolving
• Act as an effective and committed team player

Experience & Qualification:-

• 1. 8 to 11 years of experience with M.Tech/M.Sc. degree inbiotechnology/Biochemical Engineering, Biochemistry, Biology or a relatedscientific discipline.
• 2. Ability to work and collaborate in cross functional teams, research,development, manufacturing in a fast pace and dynamic team setting.