Scientist / Senior Scientist - Research & Development

Immuneel Therapeutics Pvt. Ltd.; Bengaluru; On-site; INR 900,000 - 1,400,000; Full time

Job summary

Immuneel Therapeutics Private Limited opportunities exist for a Scientist/Senior Scientist in Research & Development. You will manage clinical trial samples, develop translational assays and support correlative analyses with clinical and manufacturing data.

The role enables compliant data generation for CAR-T programs, supports assay qualification, and collaborates with cross-functional teams to advance Immuneel’s pipeline in India.

Qualifications

• Masters degree in Life sciences, Biotech or related fields with 2-4 years of industry experience.
• PhD with 1-2 years of diagnostic or industry experience.

Responsibilities

• Processing of patient samples from clinical trials and handling of PBMC, DNA, plasma, serum.
• Executing Molecular, cell biology and immuno-assays on clinical trial samples and other programs.
• Drive assay development and qualification for clinical trials and pipeline projects, inhouse or with partners.
• Analysis, reporting and review of data generated from various assays.
• Documentation: protocols, reports, and change controls; CAPA where applicable.
• Ordering of reagents and inventory management.
• Equipment management and coordination with QA/FAO for maintenance.
• Support Life cycle management activities for QARTEMI.

Skills

Detail oriented

Analytical & problem solver

Independent but team-player

Adaptable & flexible

Result-oriented

Cross-functional collaboration

Education

MSc/MS/MTech in Life Sciences/Biotech

PhD with 1–2 years diagnostic/industry exp

Tools

qPCR

ddPCR

Flow cytometry

Cell culture

Job description

Immuneel Therapeutics Private Limited is a pioneering start-up company leading the charge in cell therapy and personalized immunotherapy for patients in India. For more details, please refer www.immuneel.com

We Pursue, with Purpose, to serve our Patients (3 Ps) by Connecting within, Collaborating globally and Creating (3 Cs) solutions. Our flexible, diverse, and vibrant team is bringing together best practices and innovations in the field of cell and gene therapy.

Working at Immuneel promises the excitement of an agile start-up on a critical mission. Proudly Indian in solutioning, yet global in outlook, we are keen to collaborate. We value diversity including in experience and perspectives. We value work-life balance and believe that having fun on the job is integral to achieving the right results. We pride ourselves on providing an open environment and our mission resonates with humanity everywhere. At Work, we are:

• Passionate in driving patient outcomes: We are passionately committed to doing the RIGHT thing to achieve the best outcomes for our patients through innovation, agility and performance orientation. We put the impact on the patient above all else.
• Responsible and accountable: We demonstrate ownership and accountability for our actions. We make timely and well-informed decisions, learning from our performance.
• Transparent, honest, and supportive in how we work together: We insist on integrity and respect for the individual. We demand excellence. Our performance management is focused on excellence through timely and constructive feed-forward.
• Inclusive and flexible: We are full of life and embrace all opportunities to collaborate and work together. We are excited about the collective knowledge and expertise that we share. “Being and thinking different” is valued.

Immuneel’s employees are integral to our quest to develop and deliver high quality engineered cell therapies in India. We believe that our culture provides an environment for employees to excel and find purpose. The strength of our team is every bit as important as our cutting-edge technology and we invest in clear compensation and comprehensive benefits for our employees. People for us, are not resources, but our capital.

If you are a talented professional, an out-of-box thinker with a zeal to help change, and passionate about healthcare, we invite you to join us and be a part of a historic initiative in India.

1. Role Title:

Scientist / Senior Scientist - Research & Development

2. Department/Function:

Research & Development- Translational Research

3. Reporting Structure:

• Reports to: Director - Research & Development
• Direct Reports: NA

4. Role Summary:

The person in this role shall manage clinical trial samples, develop, qualify and run relevant translational assays. Further, the person shall also support correlative analysis with clinical and manufacturing data, In addition, the person shall support other R&D programs for development, qualification and execution of assays as required. The role shall enable compliant & Smooth Clinical Trial Data generation as well as provide support to inhouse R&D Programs.

5. Key Responsibilities:

• Processing of patient samples from clinical trials (Eg. Isolation of PBMC, DNA, Plasma, Serum etc.), storage, inventory management and reconciliation of samples.
• Executing Molecular, cell biology and immuno-assays on Clinical trial samples as well as samples from other R&D Programs (Eg. ddPCR, Flow cytometry, other cell-based assays).
• Drive Assay Development and Qualification (Cell based assays, Immunoassays, Molecular biology assays) for Clinical trials and pipeline R&D programs either inhouse or with outsourced partners.
• Analysis, Reporting and Review of Data generated from various assays.
• Industry standard Documentation: Experimental records, Protocols and Reports. Support XOP generation and closure of change controls, CAPA etc.
• Ordering of reagents, consumables, and inventory management.
• Equipment management: Support purchase and maintenance of equipment and associated documentation, co-ordination with FAO, QA for same.
• Support Life cycle management (LCM) activities for QARTEMI.
• Support any other R&D projects as required.

6. Primary Objectives:

• Ensure timely and accurate Translational data generation for CAR-T clinical trials to support approval of the therapy (Eg. IMN-003A- QARTEMI for B-ALL and IMN-006).
• Support Life cycle management activities of QARTEMI for cost reduction or business continuity.
• Work cross-functionally to develop assays and generate data for Immuneel’s pipeline programs to take them to next stage.
• Handling and processing of human blood and tissue samples.
• Experience in Molecular biology assays like qPCR, ddPCR
• Experience with Human/Mammalian cell culture
• Experience with flow cytometry.
• Basic statistical and data analytical skills.
• Experience in immunoassays (eg. ELISA) shall be bonus
• Experience in CAR-T/Cell and Gene therapy shall be bonus.
• Soft Skills:
• Expert with MS Office (Excel, word).
• Independent but Team-player
• Adaptable & Flexible
• Result-oriented
• Detail oriented & Conceptual
• Analytical & Problem solver
• Enthusiastic & Committed
• Hard working & Continuous learner

8. Qualifications:

• Masters degree (MSc, MS, MTech, MLT) in Life sciences, Biotech or related fields with 2-4 years of industry experience.
• PhD with 1-2 years of diagnostic or industry experience.

9. Working Conditions:

• Role Type: Full Time and Onsite
• Work Hours: General Shift but sometimes may require staying late or coming on weekends depending on when patient sample arrives.
• Travel Requirements: No