Scientist 2

Aurigene; Bengaluru; On-site; INR 1,200,000 - 2,400,000; Full time

Job summary

Aurigene in Bengaluru seeks an experienced pharmacometric modeling expert to lead PK/PD modelling efforts for drug development and regulatory submissions. The role involves building advanced models, collaborating with clinical pharmacology and biostatistics, and delivering model-based dosing strategies.

The candidate will work with PBPK, PopPK, QSP tools, and perform First-in-human dose predictions, ensuring quality and regulatory readiness of analyses and reports.

Qualifications

• Experience in development and application of pharmacometric models to support drug development and regulatory submissions.
• Extensive experience with non-linear mixed effects modelling.
• Proficient with software tools like PBPK models, Phoenix, R, PopPK, QSP modelling or similar platforms.
• Strong background in PK/PD modelling and First-in-human dose predictions.
• Collaborate with clinical pharmacology, biostatistics, and other interdisciplinary teams to inform trial designs and data analysis.
• Develop and implement model-based strategies to optimize dosing regimens and therapeutic outcomes.
• Ensure accuracy and quality of pharmacometric analyses and reports.
• Engage with regulatory agencies and prepare regulatory submission documents related to pharmacometric analyses.
• Stay abreast of latest developments in pharmacometrics and incorporate new methodologies and technologies as appropriate.
• Present findings and strategies to the project team and cross-functional teams.

Responsibilities

• Develop and maintain pharmacometric models to support drug development.
• Apply nonlinear mixed-effects modelling to analyse PK/PD data.
• Use PBPK and other tools to inform dose selection and trial design.
• Collaborate with clinical and statistics teams on study analyses.
• Prepare model-based reports for regulatory submissions.
• Keep up with new methods in pharmacometrics and apply where suitable.
• Present results to project teams and cross-functional stakeholders.
• Ensure high-quality, reproducible analyses and documentation.

Skills

PK/PD

Education

MSc

MPharm

PhD

Tools

PBPK models

Phoenix

R

PopPK

QSP modelling

Job description

Posted On 03 Apr 2026

End Date 22 Apr 2027

Required Experience 2 - 8 years

Skill

PK/PD DMPK

Masters of Science (M Sc) M Pharm Ph D

Highest Qualification (Discipline)

Pharmacology & Toxicology Pharmaceutical Sciences Pharmaceutics (PK& Biopharmaceutics)

Job Description

• Experience in the development and application of pharmacometric models to support drug development and regulatory submissions
• Extensive experience with non-linear mixed effects modelling
• Proficient with software tools like PBPK models, Phoenix, R, PoPK, QSP modelling or similar platforms
• Strong background in pharmacokinetics/pharmacodynamics (PK/PD) modelling and First-in-human dose predictions.
• Collaborate with clinical pharmacology, biostatistics, and other interdisciplinary teams to inform clinical trial designs and data analysis
• Develop and implement model-based strategies to optimize dosing regimens and therapeutic outcomes
• Ensure the accuracy and quality of pharmacometric analyses and reports
• Engage with regulatory agencies and prepare regulatory submission documents related to pharmacometric analyses
• Stay abreast of the latest developments in pharmacometrics and incorporate new methodologies and technologies as appropriate
• Present findings and strategies to the project team meeting and cross-functional teams. Ability to work effectively in a team environment.