Research Scientist - Cellular Engineering

Pandorum Technologies; Bengaluru; On-site; INR 781,200 - 1,060,200; Full time

Job summary

A biotechnology company based in Bengaluru is seeking a highly qualified candidate with a PhD and extensive postdoctoral experience to design and develop non-viral nucleic acid delivery systems. The role requires at least five years of hands-on experience in nanoparticle synthesis, mammalian cell culture, and various biochemical techniques. Ideal candidates will have strong skills in developing protocols and a passion for advancing RNA therapeutics. This position offers a dynamic work environment focused on innovative research.

Qualifications

• PhD with two years of postdoctoral experience required.
• Minimum of 5 years experience in nucleic acid delivery and characterization.
• Experience with mammalian cell culture and cell-based bio-assays necessary.

Responsibilities

• Design and develop non-viral nucleic acid delivery systems.
• Assist in nanoparticle characterization techniques.
• Develop and optimize protocols for cell and molecular biology studies.

Skills

Nucleic acid delivery

Nanoparticle characterization

Cell culture

Protein purification

Data analysis

Education

PhD in relevant fields

Tools

DLS

NTA

TEM

RT-PCR

ELISA

Job description

Overview

• Design and develop non-viral nucleic acid delivery systems, with a focus on platforms for next-generation RNA therapeutics.
• Assist in nanoparticle characterization techniques like DLS, NTA, TEM and RiboGreen/qPCR-style Encapsulation Assays.
• Assist in primary cell culture, including stem cell culture, cell-based functional assays, transfection through lipid or polymer-based systems, imaging such as immunofluorescence and confocal microscopy, and involvement in production of cell-derived products.
• Develop/optimize microfluidic based mixing methodologies for nucleic acid encapsulation.
• Develop and optimize protocols for various cell and molecular biology studies, such as RNA preparation and RT-PCR.
• Protein purification, characterization and analysis by ELISA, SDS-PAGE, western blot, and other biochemical techniques.
• Perform animal experiments, if required.
• Generate data for company newsletter, website, social media, printed journals, etc.
• Analyze data and prepare reports.
• Prepare SOPs for various experimental procedures.
• Prepare data for internal and external presentations, communications and publications.
• Participate in team meetings and scientific discussions.

Qualifications

PhD with two years of postdoctoral experience in the fields of Drug Delivery, Nanobiotechnology, Biochemistry, Molecular Biology, and Cell Biology, along with a minimum of 5 years of experience in nucleic acid delivery, nanoparticle synthesis/characterization, mammalian cell culture, cell-based bio-assays, quantitative RT-PCR, and ELISA, are mandatory requirements for this role.