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St John's in Bengaluru is seeking a Project Technical Support for the I-ICMR Smart RA Project on a contract basis. Aimed at individuals with 2–3 years of clinical or research experience, the role focuses on screening, recruitment, and coordination of study activities.
The position includes data management, quality control, and participant counselling/retention, with a tentative joining date of 15th November 2026. Fluency in English and local languages is preferred.
Home / Careers / Project Technical Support - I- ICMR - Smart RA Project
Employment Type: Contract
Experience: 2–3 years of clinical or research experience
Rheumatoid Arthritis affects approximately 0.5–1% of the adult population, translating into a substantial disease burden and contributing disproportionately to societal disability. Methotrexate monotherapy is the standard first-line treatment; however, it leads to only 30–50% achieving low disease activity and most patients require addition of other DMARDs (conventional, biologic or targeted-synthetic). Initiating treatment with combination of methotrexate and hydroxychloroquine, may improve efficacy by 10–20%; partly by increasing methotrexate levels. In addition, hydroxychloroquine has favorable metabolic effects like lipid lowering. Despite widespread use, robust adequately powered randomized evidence comparing first-line methotrexate monotherapy with methotrexate–hydroxychloroquine combination is lacking. This proposed study is a Sequential step-up strategy trial that mirrors real-world decision making and aims to answer two clinically relevant questions in one study with a resource-efficient framework: (i) the optimal initial csDMARD strategy, and (ii) the most effective step-up approach in patients with inadequate response. By generating pragmatic and contextually relevant evidence, this study has the potential to directly inform treatment algorithms in resource-constrained settings.
Salary : Rs.23,400/- p.m
No of Vacancy : One
Preferred Qualifications:Graduate
Age Limit: 28 Years
Preferred Language: English, Kannada, Tamil, Telugu
Tentative Date of Joining : 15thNovember 2026