Project Research Scientist -I (Bioinformatician) - ICMR CAR MANASI Project

St John's; Bengaluru; Sur place; INR 739 000 - 886 000; Temps partiel

Résumé du poste

St John's invites applications for a Project Research Scientist -I (Bioinformatician) on a contract basis in Bengaluru. The role focuses on identifying genetic factors linked to maternal DNL and infant body fat, and how they interact with the gut microbiome.

You will perform GWAS, Mendelian randomization analyses, and develop polygenic risk scores, while analyzing metagenomic data using PLINK, R, Python, and QIIME. English and Kannada are preferred language skills.

Qualifications

• Master’s degree in Bioinformatics, Biostatistics, Computational Biology, Statistical Genetics, or related field.
• Preference for candidates with GWAS, PRS, and microbiome analysis experience.
• English and Kannada language skills preferred.

Responsabilités

• Perform GWAS using large-scale genotypic and phenotypic data.
• Conduct Mendelian randomization analyses to infer causal relationships.
• Develop, validate, and apply polygenic risk scores for disease prediction.
• Process and analyze microbiome metagenomic data (taxonomic profiling, diversity, pathways).
• Ensure data quality control, imputation, and statistical modelling workflows.
• Collaborate with scientists to interpret bioinformatics results translationally.
• Maintain reproducible workflows using open-source tools (PLINK, R, Python, MR-Base, QIIME).
• Contribute to publications, reports, and grant deliverables.
• Support development of a project database integrating genetic, microbiome, and clinical data.

Connaissances

GWAS

PRS

Microbiome analysis

Data QC

Formation

Master’s degree in Bioinformatics/related field

Outils

PLINK

R

Python

MR-Base

QIIME

Description du poste

Home / Careers / Project Research Scientist -I (Bioinformatician) - ICMR CAR MANASI Project

Project Research Scientist -I (Bioinformatician) - ICMR CAR MANASI Project

Employment Type: Contract

Experience: Both freshers and experienced may apply, preference for those with experience.

Job Summary:

Identifying genetic factors underlying maternal de novo lipogenesis (DNL) and infant body fat and its interaction with gut microbiome.

Salary : RS. 72,800/- p.m

No of Vacancy :One

Key Responsibilities:

• Perform genome-wide association studies (GWAS) using large-scale genotypic and phenotypic datasets.
• Conduct Mendelian randomization analyses using the UK Biobank dataset and infer causal relationships between genetic variants, biomarkers, and disease outcomes.
• Develop, validate, and apply polygenic risk scores (PRS) for prediction of disease risk and stratification of individuals.
• Process and analyze microbiome whole metagenome sequencing data, including taxonomic profiling, diversity metrics, and functional pathway analysis.
• Implement rigorous data quality control, imputation, and statistical modeling pipelines.
• Collaborate with project coordinators, molecular biologists, nutrition scientists, and clinicians to interpret bioinformatics results in a translational context.
• Maintain and document reproducible workflows using open-source bioinformatics/statistical tools (e.g., PLINK, R, Python, MR-Base, QIIME).
• Contribute to preparation of publications, reports, presentations, and grant deliverables.
• Support the development of a project-specific database/knowledge base integrating genetic, microbiome, and clinical information.

Eligibility Criteria:

Preferred Qualifications: Master’s degree in Bioinformatics, Biostatistics, Computational Biology, Statistical Genetics, or a related field. Preference for candidates with experience in GWAS, PRS, and microbiome analysis.

Age Criteria : 35 Years

Experience : Both freshers and experienced may apply, preference for those with experience.

Preferred Language: English and Kannada

Tentative Date of Joining : 15th November 2026