Principal Systems Engineer – Clinical Computation Platform

Amgen Inc. (IR); Hyderabad; On-site; INR 3,500,000 - 5,500,000; Full time

Job summary

Amgen is seeking a Senior Systems Engineer to design, integrate, and manage complex hardware–software systems within the company’s cloud infrastructure in Hyderabad. You will collaborate with cross‑functional teams to deploy advanced technologies and ensure reliable operation of critical platforms.

The role focuses on architecture design, automation, rapid POC development, system validation, and thorough documentation.

Qualifications

• Master’s or Bachelor’s degree in Computer Science, IT, or a related field.
• 13–17 years of experience in a technology/IT role.
• Experience with AWS cloud platform and container tech (Docker, Kubernetes).
• Hands-on troubleshooting, reliability and performance improvements.
• Proficiency in Python and R for automation and data tasks.
• Knowledge of POSIT Tools and Services.
• Strong understanding of Agile, Scrum, and DevOps.
• Experience with systems integration and validation.
• Understanding of Clinical Development domain.

Responsibilities

• Collaborate with partners and engineers to deploy advanced technologies for product optimization.
• Ensure applications align with architectural and development guidelines.
• Design, build, and develop rapid POC automated solutions and services.
• Iteratively prove concepts and assess feasibility.
• Develop systems architecture to meet current and future needs.
• Integrate hardware and software into cohesive systems.
• Perform system testing and validation for correct operation.
• Optimize performance and troubleshoot issues in production.
• Create and maintain documentation of system designs and procedures.
• Coordinate with IT staff and project managers for successful implementations.
• Monitor and maintain systems for reliability and efficiency.
• Implement automation to improve system efficiency and reliability.
• Conduct training and workshops for business teams on best practices.

Skills

Python

R

Agile methodologies

Scrum

DevOps practices

Systems engineering

Communication skills

Education

Master’s / Bachelor’s degree in Computer Science / IT or related field

Tools

AWS

Docker

Kubernetes

POSIT Tools

CI/CD pipelines

Job description

ABOUT AMGEN

Amgen harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier, fuller and longer. We discover, develop, manufacture and deliver innovative medicines to help millions of patients. Amgen helped establish the biotechnology industry more than 40 years ago and remains on the cutting-edge of innovation, using technology and human genetic data to push beyond what’s known today.

ABOUT THE ROLE

The role is responsible for the design, integration, and management of complex systems that encompass both hardware and software components into the organization’s cloud infrastructure. This individual will be responsible for all activities related to handling and supporting the Business and platforms including system administration, as well as incorporating new technologies under the challenge of a sophisticated and constantly evolving technology landscape. This role involves ensuring that all parts of a system work together seamlessly to meet the organization’s requirements.

Roles & Responsibilities

• Collaborate with business partners and other software engineers to develop and deploy the latest, advanced technologies in support of product optimization


• Work closely with the delivery and platform teams to ensure that the applications are aligned with standard city planning approved architectural and development guidelines


• Support selected efforts to design, build, and develop rapid Proof-of-Concept (POC) automated solutions and services


• Quickly and iteratively prove or disprove the concepts being considered


• Develop and design systems architecture, ensuring that it meets both current and future needs of the organization


• Integrate hardware and software components into a cohesive system that meets functional and performance requirements


• Perform system testing and validation to ensure all components function correctly and efficiently


• Optimize system performance and troubleshoot any issues that arise during system operation


• Create and maintain comprehensive documentation of systems design, configurations, and procedures


• Work closely with other engineers, IT staff, and project managers to ensure successful implementation of systems


• Monitor and maintain systems to ensure they continue to operate effectively and efficiently


• Implement automation tools and processes to improve the efficiency and reliability of the system


• Conduct training and workshops for business teams to share best practices in the industry

Basic Qualifications and Experience

• Master’s / Bachelor’s degree with 13 - 17 years of experience in Computer Science, IT or related field


• Experience in cloud platforms including AWS


• Experience with container technologies like Docker and Kubernetes


• Hands‑on experience with computerized systems including troubleshooting, reliability, and performance improvements


• Experience with translating business requirements to technical requirements and recommend solutions for automation


• Proficiency in programming languages including R, Python


• Experience and strong knowledge of POSIT Tools and Services


• Strong understanding of software development methodologies, including Agile and Scrum


• Experience with DevOps tools and practices


• Strong understanding of systems engineering processes and methodologies


• Experience with systems integration and validation


• Knowledge of Clinical Development domain

Professional Certifications

• Scaled Agile Framework (SAFe) for Teams (preferred)

Soft Skills

• Excellent analytical and troubleshooting skills


• Strong verbal and written communication skills


• Ability to work effectively with global, virtual teams


• High degree of initiative and self‑motivation


• Ability to manage multiple priorities successfully


• Team‑oriented, with a focus on achieving team goals


• Strong presentation and public speaking skills

Shift Information

This position requires you to work a later shift and may be assigned a second or third shift schedule. Candidates must be willing and able to work during evening or night shifts, as required based on business requirements.

EQUAL OPPORTUNITY STATEMENT

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit www.amgen.com and follow us on www.twitter.com/amgen