Principal Scientist - Immunogenicity Research Laboratory

Syngene International Limited; Bengaluru; On-site; INR 1,200,000 - 1,800,000; Full time

Job summary

Syngene International Limited in Bangalore seeks a Principal Scientist – Immunogenicity Research Laboratory to lead bioanalysis, focusing on PK and immunogenicity assays. You will ensure strict SOP and regulatory compliance while driving data integrity and study execution.

The role requires hands-on LBA development/validation, ELISA and MSD proficiency, and collaboration with QC/QA, study directors, and cross-functional teams. Strong written and oral English skills are essential.

Qualifications

• Master’s degree in Biological Sciences with immunoassay lab experience (Biochemistry background preferred).
• Hands-on experience in Ligand Binding Assay (LBA) development, validation and sample analysis; ELISA/ MSD knowledge desirable.
• Regulatory awareness: OECD, GXP, 21 CFR Part 11, EMA, FDA guidelines.
• CRO experience preferred; manuscript writing is advantageous.
• Proficiency with LIMS, GraphPad, and data interpretation tools.

Responsibilities

• Ensure bioanalytical lab activities comply with SOPs and regulatory guidance.
• Collaborate with Study Director, QC, QA during data review and archival.
• Plan project execution, document data, analyze, interpret and present results.
• Complete assigned tasks in a timely manner.
• Prepare SOPs, protocols, methods and reports.
• Prepare reagents and logs for assays.
• Interpret results and address assay issues.
• Participate in data discussions and presentations.
• Maintain EHS requirements in the workplace.
• Attend EHS training imparted by the company.

Skills

Immunoassay

LBA development

PK & Immunogenicity assays

ELISA

MSD assays

LIMS

GraphPad

Education

Master’s degree in Biological Sciences

Tools

LIMS

GraphPad

Adobe

Job description

Date: 2 Jul 2026

Location: Bangalore, KA, IN, 560100

Division: Discovery Services

Job Title

Principal Scientist – Immunogenicity Research Laboratory

Job Location

Bangalore

Department

Translational And Clinical Research

Job Purpose

The position holder is responsible for performing bioanalysis, which includes performing ligand binding assays related to Pharmacokinetics and Immunogenicity.

Key Responsibilities

• Ensure activities conducted in the bioanalytical lab are in compliance with established SOPs, procedures, systems, regulatory guidance without deviating from established procedures.
• Regular interaction and participation with Study director, Quality Control (QC) and Quality Assurance (QA) during raw data and reports review, closure of observations and archival.
• Will be involved in strategic planning for project execution, documentation of data, data analysis, interpretation and presentation of the results.
• Ensure to complete the assigned tasks in timely manner.
• Actively involved in preparation of SOPs, protocols, method and reports.
• Prepare reagents, buffers and maintain log book for assigned assays.
• Interpret results – anticipate and understand the issues related to the assay.
• Participate in, and present data for discussions.
• Follow environment, health, and safety (EHS) requirements at all times in the workplace ensuring individual and lab/plant safety.
• Attend training on environment, health, and safety (EHS) measures imparted company.

Educational Qualification

Master’s degree in Biological Sciences (Preferably Biochemistry background) or a related field.

Technical/Functional Skills

• Should have a strong background in immunoassay and bioanalytical Pharmacokinetics and Immunogenicity Assays with a good understanding as per regulatory guidance/ industry practices/internal Standard Operating Protocols.
• Should have hands‑on experience in Ligand Binding Assay (LBA) development, validation and Sample analysis. Knowledge of ELISA and MSD assays are highly desirable.
• Knowledge and experience with regulatory requirements e.g. Organization for Economic Co-operation and Development (OECD), GXP, 21 CFR Part 11, European Medicines Agency (EMA) and Food and Drug Administration (FDA) guidelines.
• Manuscript writing ability is preferable.
• Proficiency in software like Laboratory Information Management System (LIMS), GraphPad, Adobe, etc.

Experience

Looking for an experienced candidate in immunoassay laboratory. (CRO experience is preferable).

Behavioral Skills

• Ability to work independently as well as with team members.
• A strong proactive and independent thinker.
• Excellent communication skills - written and oral in English.
• Should have good interpersonal skills.
• Large degree of flexibility and ability to work under strong time pressure.

Equal Opportunity Employer

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodation for qualified individuals with disabilities.