Openings For Formulation Development- Oral Solids

MSN Group; Hyderabad; On-site; INR 900,000 - 1,500,000; Full time

Job summary

MSN Laboratories Pvt. Ltd. in Hyderabad is seeking an Executive/Senior Executive/Junior Manager to drive Oral Solid Dosage (OSD) formulation development.

You will lead pre-formulation, prototype development, and process optimization for robust, scalable, and regulatory-compliant products. Collaborating with Analytical R&D, IPQA, Production, QC, Regulatory Affairs and Packaging, you will manage scale-up, stability studies, troubleshooting and technology transfer to ensure timely delivery of

Qualifications

• Qualification: M.Pharm / B.Pharm in Pharmaceutics, Industrial Pharmacy, Pharmaceutical Technology, or related specialization.

Responsibilities

• Execute and/or lead OSD formulation development activities including pre-formulation, prototype development, formulation optimization, process development, scale-up, exhibit/registration batches, stability studies, troubleshooting and technology transfer.
• Collaborate with Analytical R&D, IPQA, Production, QC, Regulatory Affairs, Packaging and cross-functional teams to ensure timely development of robust, scalable and regulatory-compliant formulations.

Skills

OSD formulation

Pre-formulation

Direct compression

Dry granulation

Wet granulation

Dissolution

Flow properties

Polymorphism

Education

M.Pharm / B.Pharm (Pharmaceutics)

Job description

Role & responsibilities

Executive / Senior Executive / Junior Manager

Company: MSN Laboratories Pvt. Ltd.

Department: Formulation Research & Development (FR&D)

Function: Oral Solid Dosage (OSD)

Experience: 28 Years

Qualification: M.Pharm / B.Pharm in Pharmaceutics, Industrial Pharmacy, Pharmaceutical Technology, or related specialization

Position Summary

The position is responsible for execution and/or leadership of Oral Solid Dosage (OSD) formulation development activities, including pre-formulation, prototype development, formulation optimization, process development, scale-up, exhibit/registration batches, stability studies, troubleshooting, and technology transfer.

The candidate will work closely with Analytical R&D, IPQA, Production, QC, Regulatory Affairs, Packaging, and other cross-functional teams to ensure timely development of robust, scalable, and regulatory-compliant formulations.

Key Responsibilities

1. Pre-Formulation & Product Development

• Conduct pre-formulation studies for APIs and excipients, including:
  • Solubility and pKa
  • Particle size and morphology
  • Bulk/tapped density
  • Flow properties
  • Compressibility
  • Polymorphism/solid-state characteristics
  • Drugexcipient compatibility
• Evaluate API characteristics and identify formulation challenges.
• Select appropriate excipients based on functionality, compatibility, product performance, and regulatory requirements.
• Develop formulation prototypes based on the QTPP and target product profile.
• Develop and optimize immediate-release and, where applicable, modified-release OSD formulations.

2. Formulation Development

• Plan and execute formulation trials for tablets and capsules.
• Develop formulations using appropriate manufacturing approaches such as:
  • Direct compression
  • Dry granulation
  • Wet granulation
  • Fluid-bed granulation
  • Pellet/multiparticulate technology, where applicable
• Optimize formulation variables to achieve desired CQAs such as:
  • Assay
  • Content uniformity
  • Dissolution
  • Related substances
  • Disintegration
  • Hardness
  • Friability
  • Weight variation
• Conduct comparative dissolution studies and support formulation selection.
• Identify and resolve formulation-related problems during development.