Lead Scientist

Syngene International; Bengaluru; On-site; INR 1,200,000 - 1,800,000; Full time

Job summary

Syngene International Ltd. in Bengaluru, India, is seeking an experienced scientist to design, develop, optimize, and execute in vitro biochemical and cell-based assays to support drug discovery programs.

The role will generate high-quality data, troubleshoot assays, and collaborate with multidisciplinary project teams. The position requires 5–8 years of experience and a Master’s degree in pharmacology or life sciences, with strong mammalian cell culture and data-analysis skills.

Qualifications

• Masters degree in pharmacology, life sciences, biotechnology or related field.
• 5–8 years of experience in drug discovery.
• Strong experience in mammalian cell culture and electrophysiology.
• Ability to design, optimize and troubleshoot biochemical and cell-based assays.
• Experience with plate-based assays, high-content imaging and data analysis.

Responsibilities

• Electrophysiology assays – patch clamping
• Design, develop, optimize, execute and troubleshoot biochemical and cell-based assays
• Independently perform experiments and generate high-quality, reproducible data.
• Compound screening, profiling, and mechanism-of-action studies in multiple therapeutic areas
• Analysis and interpretation of experimental data
• Presentation and communication of data to stakeholders
• Following Syngene’s data quality, integrity and EHSS guidelines
• Maintain accurate documentation and comply with quality, data integrity, and EHSS standards

Skills

Mammalian cell culture

Electrophysiology

Biochemical assay design

Cell-based assays

High content imaging

Data analysis

Education

Masters in pharmacology / life sciences/ biotechnology/ biological engineering

Tools

GraphPad Prism

Job description

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Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene's clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240-strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation .

Job Purpose (1-2 Lines)

Experienced and highly motivatedscientistto design, develop,optimize, and execute in vitro biochemical and cell-based assays in support of drug discovery programs.Responsible for generating high-quality data, troubleshooting assays, analyzing results, communicating to stakeholders and collaborating with multidisciplinary project teams.

Key Responsibilities:

• Electrophysiology assays – patch clamping
• Design, develop,optimize, execute and troubleshoot biochemical and cell-based assays
• Independently perform experiments and generate high-quality, reproducible data.
• Compound screening, profiling, and mechanism-of-action studies in multiple therapeutic areas
• Analysis and interpretation of experimental data
• Presentation and communication of data to stakeholders
• Following Syngene’s data quality, integrity and EHSS guidelines
• Maintainaccuratedocumentation andcomply withquality, data integrity, and EHSS standards

Educational Qualification: Masters in pharmacology / life sciences/ biotechnology/ biological engineering

Experience: 5-8 years of working in drug discovery industry

Technical/functional Skills:

• Strong experience in mammalian cell culture
• Electrophysiology – patch clamping,
• Hands-onexpertisein biochemical and cell-based assay design and development.
• Plate-based assays, immunofluorescence/ high content imaging, microscopy and automation,
• Proficiencyin GraphPad Prism or similar tools for basic data analysis
• Experience with primary cells and/or iPSC-derived cellular models.

Behavioral Skills: Strong problem-solving and troubleshooting skills, high attention to detail and commitment to data quality, excellent written and verbal communication skills along with good presentation skills. Ability to handle multiple projects simultaneously and meet aggressive project timelines. Ability to work independently and collaboratively in a multi-disciplinary team. Must demonstrate integrity , accountability, and scientific curiosity.

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodation for qualified individuals with disabilities.