Upstream Bioprocess Research Associate II

biomarin; Cork; On-site; EUR 40,000 - 60,000; Full time

Job summary

BioMarin is hiring a Research Associate 2 to support upstream bioprocess development at our Cork site. You will collaborate with cross-functional teams to perform and document scientific experiments, contributing to BCoE studies and the portfolio of therapies for rare diseases.

The role demands strong attention to detail, good data handling, and a proactive approach to troubleshooting. Occasional weekend work may be required to meet project timelines.

Responsibilities

• Executes defined procedures independently to support BCoE studies and downstream lab processes.
• Demonstrates quick learning of core techniques, principles, and protocols; owns small project portions with reliable execution and summarizes findings.
• Understands the principles of aseptic operation and has experience working in biosafety cabinets.
• Possesses experience in daily operations with microbial cell culture (E. coli), including: Cell thawing, Cell banking, Seed train expansion.
• Has experience in fermentation processes, including: Fermenter inoculation, Daily monitoring, Sampling, In-process analysis utilizing standard bioprocess analytical equipment.
• Has a basic understanding of mammalian cell expansion and its differences compared to microbial operations.
• Experience in processing of inclusion bodies is desirable.
• Produces accurate, reproducible data entries and maintains laboratory quality through adherence to safety standards and SOPs; able to troubleshoot common problems with guidance.
• Expands technical toolkit by adapting and troubleshooting process steps or assays; applies appropriate methods and interprets basic data trends.
• Updates and refines SOP/BPD documentation.
• Assists in drafting concise technical summaries.
• Understanding of fed-batch and perfusion bioprocesses is desirable.
• Experience in depth filtration and ultrafiltration is desirable.
• Understanding of downstream purification processes is desirable.
• General Responsibilities: Executes and completes projects independently; Generates and reviews data; performs data analysis; Maintains up-to-date documentation; Supports updates of lab instructions and templates; Supports maintenance/calibration of lab equipment; Contributes to evaluation of new equipment; Acts as a team player; Maintains workplace and laboratory safety; Complies with GxP regulations and SOPs; May work outside normal hours including weekends.

Job description

BioMarin is hiring a Research Associate 2 to support upstream bioprocess development at our Cork site. You will collaborate with cross-functional teams to perform and document scientific experiments, contributing to BCoE studies and the portfolio of therapies for rare diseases.

The role demands strong attention to detail, good data handling, and a proactive approach to troubleshooting. Occasional weekend work may be required to meet project timelines.