Senior Clinical Data Manager — Hybrid (12-Month Contract)

Zymeworks Inc.; Swords; Hybrid; EUR 90,000 - 120,000; Full time

Job summary

Zymeworks Inc. is seeking a Clinical Data Manager for a 12‑month contract based in Dublin, Ireland.

The role is hybrid with a minimum of three onsite days weekly and involves leading data management activities for studies, collaborating across functions, and ensuring high-quality data and regulatory compliant deliverables. Responsibilities include DM lifecycle management, CRF development, edit checks, UAT, and data cleaning.

Qualifications

• Degree plus 8+ years experience in clinical data management or equivalent.
• Strong knowledge of FDA regulations, ICH GCP, and data standards (SDTM, CDISC).
• Experience with electronic data capture (EDC) systems and data review.
• Preferred: ePRO, SharePoint, J-Review, BI tools; programming experience.

Responsibilities

• Oversee data management activities with vendors/CROs to ensure high quality outcomes.
• Represent Zymeworks on cross-functional study teams.
• Develop/review data management documents (CRFs, DMPs, edit checks).
• Execute DM lifecycle tasks from start-up to close-out, including testing and query management.
• Lead data cleaning to meet study timelines.
• Maintain DM metrics and project documentation.
• Contribute to process improvements and SOPs.
• Manage third-party data reconciliations.

Skills

FDA regulations

GCP guidelines

Data management

Programming

Cross-functional collaboration

Education

BA or BS in a related field

Tools

EDC

IXRS

RTSM

Medidata Rave

SharePoint

J-Review

Job description

Zymeworks Inc. is seeking a Clinical Data Manager for a 12‑month contract based in Dublin, Ireland.

The role is hybrid with a minimum of three onsite days weekly and involves leading data management activities for studies, collaborating across functions, and ensuring high-quality data and regulatory compliant deliverables. Responsibilities include DM lifecycle management, CRF development, edit checks, UAT, and data cleaning.