Remote Pharmacometrics Data Programmer (R, NONMEM)

ICON Clinical Research Ltd; Dublin; On-site; EUR 90,000 - 120,000; Full time

Benefits offered by this job

Health insurance

Pension plan

Life assurance

Disability cover

Employee assistance program

Learning and development opportunities

Job summary

ICON Clinical Research Ltd is seeking an experienced Pharmacometrics Support Programmer to join a global FSP team. You will develop and quality control NONMEM PK/PD datasets, support modelling activities, and ensure data quality for regulatory submissions.

The role requires strong R programming skills, extensive PK/PD knowledge, and experience with CDISC standards, across a multinational pharmacometrics environment. Fluency in English is essential.

Qualifications

• Bachelor's degree in Life Science, Health Science, Statistics, Computer Science, IT, or related discipline.
• Minimum of 6 years' experience within the pharmaceutical, biotechnology, or CRO industry.
• Strong programming expertise in R.
• Experience developing and quality controlling NONMEM PK/PD datasets.
• Working knowledge of PK/PD principles and pharmacometric workflows.
• Strong understanding of SDTM, ADaM, and CDISC standards, including controlled terminology.
• Experience supporting NONMEM file creation, quality control, submissions, and standardisation activities.
• Strong attention to detail and commitment to data quality.
• Excellent written and verbal communication skills in English.

Responsibilities

• Develop and quality control NONMEM PK/PD datasets using SDTM and ADaM data sources.
• Support pharmacometric modelling activities by delivering accurate, complete, and submission-ready datasets.
• Perform quality review of internally and externally produced NONMEM datasets.
• Collaborate with Data Management, Statistical Programming, Statistics, Clinical Pharmacology, and Bioanalytical teams to resolve data issues and ensure project timelines are met.
• Contribute to the preparation of regulatory submission projects in accordance with internal pharmacometrics guidelines.
• Conduct quality control testing of customised R packages used to standardise pharmacometric workflows.
• Develop and maintain testing frameworks and validation processes for departmental R tools and packages.
• Identify data discrepancies, process improvements, and opportunities for greater automation and efficiency.
• Actively contribute to the development and implementation of new pharmacometric standardisation initiatives.
• Ensure all deliverables comply with applicable SOPs, working instructions, regulatory requirements, and ICH‑GCP guidelines.
• Maintain inspection readiness through ongoing training and adherence to quality standards.

Skills

R programming

NONMEM PK/PD datasets

Data quality

Regulatory submissions

PK/PD workflows

SDTM/ADaM/CDISC standards

English communication

Education

Bachelor's degree in Life Science or related

Tools

R packages testing

Job description

ICON Clinical Research Ltd is seeking an experienced Pharmacometrics Support Programmer to join a global FSP team. You will develop and quality control NONMEM PK/PD datasets, support modelling activities, and ensure data quality for regulatory submissions.

The role requires strong R programming skills, extensive PK/PD knowledge, and experience with CDISC standards, across a multinational pharmacometrics environment. Fluency in English is essential.