Senior Statistical Programmer

ICON Clinical Research Ltd; Ireland; On-site; EUR 90,000 - 120,000; Full time

Benefits offered by this job

Health and wellbeing programmes

Retirement and pension plans

Life assurance and disability coverage

Learning and development opportunities

Job summary

ICON is seeking a Senior Statistical Programmer to lead R-based analyses and develop CDISC-compliant datasets for clinical trials. You will drive quality, collaborate with biostatisticians, and support regulatory submissions.

The role requires strong R skills, SDTM/ADaM knowledge, and experience in a clinical research or biotech environment. You’ll work within a diverse team focused on delivering high-quality study results.

Qualifications

• Bachelor's or Master's degree in Statistics, Mathematics, Computer Science, Life Sciences, or related quantitative field.
• Experience in statistical programming within a clinical research, biotechnology, or pharmaceutical environment.
• Strong proficiency in R programming for datasets, analyses and reporting outputs.
• Good understanding of CDISC SDTM and ADaM standards and their application in trials.
• Familiarity with regulatory requirements and industry guidance for statistical programming.

Responsibilities

• Develop and validate R programs for statistical analysis and reporting of clinical trial data.
• Lead more than one Programming team to create, validate and generate outputs (SDTM/ADaM compliant).
• Collaborate with biostatisticians to define analyses and methods.
• Perform quality control and validation of statistical outputs for regulatory submissions.
• Assist in preparing statistical reports and publications for study reporting.

Skills

R programming

CDISC SDTM/ADaM

Statistical analysis

Team leadership

Regulatory compliance

Biostatistics collaboration

Education

Bachelor's or Master's in Statistics, Mathematics, CS, Life Sciences

Job description

Senior Statistical Programmer - R ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

We are currently seeking a Senior Statistical Programmer to join our diverse and dynamic team. As a Senior Statistical Programmer at ICON, you will play a crucial role in analyzing clinical trial data and supporting the statistical analysis process to ensure high-quality results. You will contribute to the success of our clinical studies by developing and validating statistical programs in R, collaborating with biostatisticians, and ensuring compliance with regulatory standards.

What You Will Be Doing:

• Developing and validating R programs for statistical analysis and reporting of clinical trial data.
• Leading more than one Statistical Programming team to create, validate and generate statistical outputs, including listings, tables, figures, and CDISC-compliant SDTM and ADaM datasets (including mapping specifications) of low to moderate complexity.
• Collaborating with biostatisticians to define analysis plans and statistical methods to be applied to clinical data.
• Performing quality control and validation of statistical outputs, ensuring accuracy, consistency, and regulatory compliance.
• Assisting in the preparation of statistical reports, presentations, and publications to support regulatory submissions and clinical study reporting.
• Contributing to process improvements by identifying efficiencies in programming practices, automation, and the use of R-based analytical workflows.
• Supporting the development, maintenance, and enhancement of standardized R programming tools, macros, and reporting solutions across studies.

Your Profile:

• Bachelor's or Master's degree in Statistics, Mathematics, Computer Science, Life Sciences, or a related quantitative field.
• Experience in statistical programming within a clinical research, biotechnology, or pharmaceutical environment.
• Strong proficiency in R programming, including the development and validation of clinical trial datasets, analyses, and reporting outputs.
• Good understanding of CDISC standards, including SDTM and ADaM, and their application within clinical trials.
• Familiarity with regulatory requirements and industry guidance related to statistical programming and clinical data reporting.
• Excellent analytical and problem-solving skills, with a keen attention to detail.
• Strong communication skills, with the ability to work collaboratively in a team environment and effectively convey complex information.

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

• Competitive base salary and performance related incentives
• Health and wellbeing programmes including medical, dental, and vision coverage where applicable
• Retirement and pension plans
• Life assurance and disability coverage
• Employee assistance programmes and wellbeing resources
• Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.

Visit our careers site to read more about the benefits ICON offers.

Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported. If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.