Maintenance & Reliability (M&R) Engineer

Amgen Foundation, Inc.; Dún Laoghaire; Remote; EUR 70,000 - 100,000; Full time

Job summary

Amgen Dun Laoghaire (ADL) is seeking a Maintenance & Reliability Engineer to improve asset uptime and maintainability across the aseptic drug product facility. You will develop robust reliability frameworks, reduce downtime, and collaborate with Engineering, Operations and Quality.

The role emphasizes data-driven maintenance, preventive and predictive strategies, and continuous improvement, with a focus on right-first-time execution, safety and regulatory compliance.

Qualifications

• Bachelor’s degree in engineering or related discipline.
• 2-3 years’ experience in a GMP manufacturing environment in maintenance or reliability.
• Ability to work across functional boundaries and influence outcomes.

Responsibilities

• Support Drug Product manufacturing in Vial and Syringe filling plants.
• Develop and modernise the maintenance PMO programme and use digital tools to enhance predictability.
• Employ analytics to assess performance and identify improvements for equipment reliability and maintenance execution.
• Develop multi-year reliability roadmap and ensure flawless execution with cross-functional partners.
• Analyse equipment data to identify chronic issues and implement sustainable improvements.
• Collaborate with system owners to define maintenance scopes and plans.
• Prioritise reliability-critical work to deliver right-first-time outcomes.
• Drive continuous improvement and embed standard work and documentation.
• Lead system improvements, create specifications and SOPs.
• Solve complex problems, manage projects, and optimise asset lifecycle.

Skills

Cross-functional collaboration

Analytical thinking

Problem solving

Technical writing

Strategic reliability planning

Education

Bachelor’s degree in engineering

Tools

CMMS/EAM systems

Lean / Six Sigma / TPM

Job description

Maintenance & Reliability (M&R) Engineer

Job Description

Amgen discovers, develops and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realise the new science’s promise by bringing safe, effective medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people’s lives.

Amgen Dun Laoghaire (ADL) is a 37,000 square metre aseptic drug product operations facility, currently undergoing expansion, specialising in secondary manufacturing activities – Formulation, Vial/Syringe Filling, Lyophilisation and Packaging. The ADL site also includes laboratories and cold chain warehouse capabilities. There is a strong culture of continuous improvement and innovation within ADL to strive for solutions that improve health outcomes and dramatically improve people’s lives. Amgen is developing the capability to produce all of its medicines in Dun Laoghaire, helping to ensure continuity of supply of our medicines as we expand internationally.

The Maintenance & Reliability (M&R) Engineer is responsible for improving the reliability, availability, and maintainability of plant equipment within the ADL manufacturing facility. The role focuses on developing and sustaining a robust reliability framework that ensures right-first-time maintenance execution, minimises unplanned downtime, and optimises asset lifecycle performance in support of safe, compliant, and efficient operations.

The role partners closely with Engineering, Operations, and Quality to analyse equipment performance, identify failure modes, and implement preventive and predictive maintenance strategies. The Maintenance Reliability Engineer also leads continuous improvement initiatives to reduce non-commercial time, improve equipment uptime, and increase overall plant availability.

Key Duties and Responsibilities

• Support Drug Product manufacturing within the Vial and Syringe filling plants.
• Develop, optimise and modernise the maintenance PMO programme to ensure equipment maintenance is maintained at the right level, frequency while also utilising digital tools to enhance predictability and targeted maintenance strategies.
• Employ business analytics to assess performance and identify improvement opportunities for Equipment Reliability, Maintenance Reliable Execution, Condition Monitoring and Predictive Maintenance.
• Develop & Design Multi-Year Reliability roadmap and ensure flawless execution with close collaboration/partnership with key cross-functional stakeholders.
• Analyse equipment performance data (e.g. downtime, failure trends, MTBF, MTTR) to identify chronic issues and implement sustainable reliability improvements.
• Collaborate with system owners, planners, and technicians to define maintenance scopes, refine job plans, and ensure maintenance tasks are technically sound, risk-based, and executable.
• Support shutdown and non-commercial time activities by ensuring reliability-critical work is correctly prioritised, scoped, and executed to deliver right-first-time outcomes.
• Drive continuous improvement through the cycle, capturing lessons learned and embedding standard work, best practices, and technical documentation into future maintenance execution.
• Lead and support system improvements, development of detailed specifications, engineering documents and standard operating procedures.
• Solving complex problems, project management, equipment lifecycle management and operational excellence.
• Support a safe working environment by complying with all pertinent environmental health/safety practice, rules and regulations.

Basic Qualifications

• Bachelor’s degree in engineering (Mechanical, Electrical, Electronic, Chemical, Software) or related scientific discipline and/or relevant experience.
• Minimum of 2-3 years’ experience in a GxP manufacturing environment in a maintenance, reliability, or an engineering type role.
• Demonstrated ability to work across functional boundaries and influence outcomes without direct authority.

Preferred Experience

• 2-3 years’ engineering or scientific experience in a pharmaceutical or biotech manufacturing environment.
• Proven experience implementing reliability improvement initiatives in complex, multi-system facilities.

Knowledge and Relevant Experience

• Strong working knowledge of pharmaceutical/biotech manufacturing and aseptic processing.
• Fundamental understanding of GxP, EHS, and regulatory compliance requirements.
• Asset reliability methodologies (RCA, FMEA, criticality analysis, PM optimisation).
• Experience with CMMS/EAM systems and data-driven maintenance decision-making.
• Application of continuous improvement tools and methodologies (Lean, Six Sigma, TPM).

Skills

• Strong collaborator who promotes a culture of reliability, accountability, and continuous improvement.
• Ability to assess and influence both short- and long-term decisions impacting equipment uptime and plant availability.
• Excellent analytical, problem-solving, and prioritisation skills.
• Strong technical writing and communication skills, with the ability to clearly convey complex technical concepts to diverse audiences.
• Ability to balance tactical execution with strategic reliability planning.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law.

We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.