Associate Director, Upstream Technical Operations Lead

Msd Ireland; Dunboyne; Hybride; EUR 150 000 - 190 000; Plein temps

Résumé du poste

MSD Ireland is seeking an Upstream Technical Operations Lead for our Dunboyne biologics facility. You will own the upstream program end-to-end, from media preparation to bioreactor operations, while leading a team of scientists and engineers in a fast-paced, regulated environment.

You will collaborate across global teams to drive strategy, technical standards, and continuous improvement, ensuring robust, compliant manufacturing and efficient operations.

Qualifications

• 8–10 years of biopharmaceutical manufacturing or development experience.
• Proven leadership in scientific/technical roles.
• Experience in GMP environments and regulatory filings.
• Experience with technology transfer, PPQ, and new product introduction.

Responsabilités

• Maintain end-to-end technical ownership of the biologics program from tech transfer to lifecycle management.
• Provide floor-based manufacturing support to resolve real-time issues and ensure compliant production.
• Lead and develop upstream scientists, engineers, and subteam leads with clear accountability.
• Collaborate with Downstream, Quality, Engineering, and Global teams to align priorities.

Connaissances

Biopharma manufacturing

People leadership

GMP compliance

Stakeholder management

Strategic thinking

Formation

B.S./M.S./Ph.D. in relevant engineering or science

Outils

Automation systems

Process automation tools

Description du poste

Job Description

Join our state-of-the-art biologics manufacturing facility in Dunboyne as the Upstream Technical Operations Lead.

In this pivotal role, you will hold end-to-end technical, manufacturing, and people accountability for a complex, growing biologics program. Reporting directly to the Upstream Technical Operations Director as part of the MSAT function, you will lead a high-performing team of scientists and engineers delivering day-to-day manufacturing support across the entire upstream process—from media preparation and cell culture to bioreactor operations, harvest, and process monitoring.

What You Will Do

Technical Program Ownership

• Maintain end-to-end technical ownership of the assigned biologics program, guiding activities from technology transfer and PPQ execution through to commercial lifecycle management.
• Act as a core member of the Upstream technical leadership team, helping to shape the site's overall technical strategy and execution standards.

Manufacturing Support & Operational Excellence

• Enable robust, compliant, and reliable production by providing visible, floor-based technical support to resolve real-time manufacturing issues.
• Set clear priorities, expectations, and decision-making frameworks to ensure rapid deviation investigations, root-cause analyses, and change implementation.
• Proactively identify, assess, and resolve manufacturing risks, establishing strong escalation practices and transparent communication with site and global stakeholders.

People Leadership & Talent Development

• Lead, coach, and develop a team of upstream scientists, engineers, SMEs, and subteam leads, ensuring clear accountabilities, capacity management, and strong engagement.
• Foster a culture of continuous learning, scientific rigor, engineering excellence, psychological safety, and lean-driven improvement.
• Mentor team members through complex problem-solving, stretch assignments, and subteam leadership opportunities to strengthen site succession plans.

Cross-Functional Collaboration

• Collaborate closely with Downstream Receiving Unit lead, Integrated Process Teams, Commercialisation partners, and the Global Biologics Organisation to align technical priorities, share best practice, and accelerate the successful delivery of a complex and evolving pipeline.
• Partner closely at the interface between Development, Quality, Engineering, Automation, Supply Chain, and global technical partners to drive strategic program delivery.

What Skills You Will Need

Education & Professional Experience

• Degree: B.S., M.S., or Ph.D. in a relevant Engineering or Scientific discipline.
• Experience: A minimum of 8–10 years of experience in biopharmaceutical manufacturing and/or development, with a proven track record in scientific and technical leadership roles.

Technical & Operational Expertise

• Upstream Processes: Deep technical expertise in biologics molecules, cell culture, seed train, bioreactor operations, media/feed strategies, harvest, process equipment, and automation.
• Product Lifecycle: Proven experience in biologics drug substance development, technology transfer, PPQ, and new product introduction.
• GMP Compliance: Strong operational experience in a highly regulated GMP environment, including regulatory filings, investigations, quality notifications, CAPA management, and audit readiness.
• Business Acumen: Solid understanding of product lifecycle management, financial stewardship, and the ability to manage resource allocation across multiple complex programs.

Leadership & Influence

• Leading Through Others: Proven ability to build, scale, and lead high-performing technical teams, setting clear priorities and coaching technical decision-making.
• Stakeholder Management: Excellent communication and presentation capabilities, with a demonstrated ability to influence and collaborate across all levels of a global network.
• Agility & Drive: A strong sense of urgency, resilience, and change agility, combined with an engaging, motivational leadership style.

Why Join Us?

• Work in a cutting-edge, state-of-the-art biologics facility in Dunboyne.
• Lead a diverse, growing pipeline of biologics programs.
• Drive technical excellence within a highly collaborative, cross-functional global network.

Additional location(s) Compensation Information:

Business Acumen, Business Acumen, Business Management, Cell Cultures, Change Adoption, Computerized Maintenance Management Systems (CMMS), Cross-Cultural Awareness, Financial Management, GMP Compliance, GMP Environments, Maintenance Supervision, Mammalian Cell Culture, Manufacturing Quality Control, Manufacturing Support, People Leadership, Pharmaceutical Development, Process Engineering, Process Improvements, Product Lifecycle, Regulatory Compliance, Regulatory Inspections, Resource Allocation, Single-Use Systems (SUS), Sterile Manufacturing, Strategic Thinking {+ 1 more}

Employee Status

Regular

Flexible Work Arrangements

Hybrid