Downstream Process Science Lab Technical Lead (Mgr.)

MSD Ireland; Dunboyne; Presencial; EUR 90.000 - 120.000; Jornada completa

Descripción de la vacante

MSD Ireland in Dunboyne, Meath seeks a Downstream Process Science Lab Technical Lead to drive the downstream team and collaborate across the site for biologics manufacturing. You will lead design, execution, and optimization of scale-down studies, with emphasis on purification, filtration, and viral clearance processes.

The role requires a science/technical degree with 6+ years in biopharma, strong GMP and data integrity knowledge, and strong cross-functional communication to enable successful

Formación

• Degree in Science or a related technical field; MSc/PhD desirable.
• Experience in biopharmaceutical development or MS&IT/process sciences is essential.
• Strong GMP knowledge and data integrity understanding.

Responsabilidades

• Lead a team of Downstream scientists overseeing scale-down model establishment and improvement studies.
• Oversee small-scale studies supporting technology transfer, facility fit, and lifecycle changes.
• Provide technical leadership for downstream purification, filtration, viral clearance, UF/DF, and formulation activities.

Conocimientos

Downstream operations

GMP knowledge

Data interpretation

Cross-functional teamwork

Problem solving

Educación

Science/Technical degree

MSc or PhD desirable

Descripción del empleo

Job Description

An exciting new opportunity has arisen for a Downstream Process Science Lab Technical Lead in Dunboyne, Co. Meath. This role is part of the Manufacturing Science and Technology (MS&T) group at our state-of-the-art, single-use, multi-product facility in Dunboyne. The Lab Technical Lead (Downstream) is responsible for contributing to the overall running of the Process Sciences Laboratory and working across site as part of a diverse and interdisciplinary team to build capability and knowledge in the manufacture of biologics at the site.

Our facility in Dunboyne is a premier, state-of-the-art facility that enables and advances our best work. By integrating leading-edge technology with a dynamic, activity-based workspace, the facility supports seamless connection and collaboration within and across teams and functions. Our Dunboyne facility provides Biologics Drug Substance manufacturing for Clinical Supply, Registration, and Commercial Launch.

We keep the patient at the very heart of all that we do and strive to find solutions and treatments for some of the world’s most challenging healthcare needs.

Key Responsibilities

• Management of a team of Downstream scientists involving the design, planning and execution of scale-down model establishment, satellite, and improvement studies in the Process Sciences Lab.
• Oversee the design and execution of small-scale studies which support Dunboyne site and CMO technology transfer, facility fit, process characterisation, and lifecycle change.
• Provide technical leadership for downstream studies supporting purification, filtration, viral clearance-related activities, UF/DF, formulation, and associated process optimisation work.
• Provision of technical expertise and leadership to support successful new product introduction across all Drug Substance programs at the site.
• Lead and coach others to solve problems and take new perspectives on existing solutions with a desire to continuously learn, improve and develop.
• Excellent troubleshooting and problem-solving skills as well as influencing, collaboration skills and teamworking ability to represent MS&T on global and interdisciplinary teams.
• Champion a proactive safety, quality, and compliance culture within all laboratory activities within an open and inclusive team culture.

Qualification & Experience Requirements

• A degree qualification in a relevant field (Science/Technical). An Advanced Degree (MSc or PhD) qualification is desirable.
• A minimum of 6 years’ experience working in biopharmaceutical development, manufacturing support, MS&T, process sciences, or technical operations, with experience in Downstream biologics operations.
• Strong understanding of GMP, regulatory expectations, data integrity, and quality systems relevant to laboratory and manufacturing support activities.
• Proven ability to interpret complex datasets, solve technical problems, and convert scientific findings into practical manufacturing actions.
• Effective communicator with the ability to think logically and be proactive under pressure and work as part of a cross-functional team.

Required Skills

Biologics, Biopharmaceuticals, Cell Cultures, Downstream Operations, Good Manufacturing Practices (GMP), Lab Processing, Manufacturing, Technology Transfer

Employee Status

Regular

Flexible Work Arrangements

Not Applicable

Job Posting End Date

11/13/2026

• A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID

R424686