Analytical Scientist

STEM Recruitment Partners; Dublin; On-site; EUR 55,000 - 90,000; Full time

Job summary

A Dublin 15-based leading pharmaceutical manufacturer seeks an Analytical Scientist for a 12-month contract to provide critical analytical support on laboratory projects, investigations, and material assessments at a state-of-the-art facility.

You will perform RP-HPLC, LC-MS, and SEC/GPC analyses, develop and troubleshoot methods, ensure GMP compliance, and contribute to data integrity and documentation across projects.

Qualifications

• PhD, MSc, or BSc in Chemistry, Biology, Engineering or related science is required.
• Minimum 3–5 years hands-on analytical laboratory experience in a regulated GMP environment.
• Experience with RP-HPLC analysis and method development for peptides or biological molecules.
• Experience operating LC-MS and interpreting mass-spectrometry data, including SEC/GPC methods.

Responsibilities

• Perform hands-on RP-HPLC analysis of peptides and biological molecules, including method development and validation.
• Develop and execute SEC/GPC methods for polymers and biologically derived polymers.
• Operate LC-MS systems and perform spectral interpretation, including MS/MS.
• First-line troubleshooting of HPLC/UPLC and LC-MS instrumentation to maintain performance.
• Review, interpret, and trend analytical data; support investigations of atypical or out-of-spec results.
• Draft and maintain SOPs, analytical methods, protocols, and qualification/validation reports with GMP compliance.

Skills

Analytical laboratory experience

Strong communication

Cross-functional teamwork

Education

PhD, MSc, or BSc in Chemistry, Biology, Engineering or related science

Tools

RP-HPLC

LC-MS

SEC/GPC

HPLC/UPLC instrumentation

Job description

We are partnering with a leading pharmaceutical manufacturer based in Dublin 15 to source an Analytical Scientist for a 12-month contract opportunity. This role offers competitive hourly rates and the chance to work within a dynamic Global Operations & Quality team, providing critical analytical support on laboratory projects, technical investigations, and material assessments at a state-of-the-art manufacturing facility.

Reporting to the Senior Manager, Technical Operations, you will perform and oversee analytical laboratory activities with a strong hands-on analytical focus. The role includes RP-HPLC, size-exclusion chromatography, and LC-MS analysis of peptide-based products, biologically derived polymers, and other complex molecules. You will develop, optimise, troubleshoot, and execute analytical methods while providing scientifically sound assessments of analytical results.

Key Responsibilities

• Perform hands-on RP-HPLC analysis of peptides, peptide-based products, and other biological or large molecules, including method development, optimisation, qualification, validation, transfer, and routine execution.
• Develop and execute size-exclusion chromatography (SEC/GPC) methods for synthetic polymers, biologically derived polymers, and other complex macromolecules.
• Operate LC-MS systems and perform sample analysis, data processing, spectral interpretation, and advanced mass analysis, including accurate-mass determination, spectral deconvolution, peptide mapping, and MS/MS interpretation.
• Perform first-line troubleshooting of HPLC, UPLC, and LC-MS instrumentation, including pumps, autosamplers, detectors, pressure problems, leaks, chromatography performance, and software-related issues.
• Review, interpret, and trend analytical data, providing scientifically justified assessments of analytical results and supporting investigations of atypical, out-of-trend, and out-of-specification results.
• Draft, review, and maintain SOPs, analytical methods, protocols, technical assessments, laboratory investigation reports, method-development reports, and validation or qualification reports while ensuring compliance with GMP, data-integrity, and laboratory documentation requirements.

Requirements

• PhD, MSc, or BSc in Chemistry, Biology, Engineering, or a related science; strong analytical background required.
• Minimum 3-5 years of hands-on analytical laboratory experience in a pharmaceutical, biopharmaceutical, or other regulated GMP environment.
• Demonstrated hands-on experience with RP-HPLC analysis and method development for peptides, peptide-based products, proteins, or other biological molecules.
• Practical experience operating LC-MS instrumentation and interpreting complex mass-spectrometry data, including experience with SEC/GPC methods for synthetic or biologically derived polymers.
• Proven ability to troubleshoot chromatography methods and perform first-line diagnosis and maintenance of HPLC, UPLC, or LC-MS equipment, with experience in analytical method development, optimisation, qualification, validation, method transfer, and lifecycle management.
• Strong working knowledge of GMP, laboratory data integrity, and good documentation practices, with excellent communication skills and the ability to work effectively in a cross-functional team environment.