Upstream Biologics Process Scientist

Blackfield Associates; Slough; On-site; GBP 42,000 - 60,000; Full time

Job summary

Blackfield Associates is seeking an Associate Scientist/Research Scientist to join a Drug Substance Process Sciences team on a 12-month contract in Slough, UK. It is a laboratory-based role focusing on upstream process development for biologics, with emphasis on mammalian cell culture, DoE and scale-up.

You will work across multidisciplinary teams, design experiments using QbD, operate Ambr systems and laboratory bioreactors, and contribute to data reporting, technology transfer and continuous

Qualifications

• MSc in Biotechnology, Biochemical Engineering, Chemical Engineering, Molecular Biology, Cell Biology, Bioprocess Engineering or related, or BSc with relevant industrial experience.
• Experience in mammalian cell culture and biologics process development.
• Hands-on experience with CHO cell culture and therapeutic protein production.
• Experience operating Ambr® systems and/or laboratory-scale bioreactors.
• Knowledge of cell culture scale-up principles and process characterisation.
• Experience applying DoE and statistical data analysis tools.
• Strong scientific problem-solving and troubleshooting skills.
• Experience with automation, digital tools and data management systems would be advantageous.
• Understanding of GMP/GSP, data integrity and quality requirements.
• Strong planning, organisational, communication and technical writing skills.

Responsibilities

• Design, plan and execute upstream process development studies using QbD and DoE approaches.
• Perform mammalian cell culture experiments using shake flasks, Ambr systems and lab bioreactors, supporting scale-up and tech transfer.
• Analyze and interpret data, prepare technical reports and project summaries, and communicate findings to teams.
• Collaborate with Cell Line Development, Analytical Sciences, Downstream Development, Manufacturing and external partners; drive continuous improvement.

Skills

Mammalian cell culture

Bioprocess development

DoE & statistics

GMP/GSP & data integrity

Scale-up & tech transfer

Automation & data management

Education

MSc in Biotechnology or related

BSc with relevant industrial experience

Tools

Ambr® systems

Bioreactors

Shake flasks

Job description

Blackfield Associates is seeking an Associate Scientist/Research Scientist to join a Drug Substance Process Sciences team on a 12-month contract in Slough, UK. It is a laboratory-based role focusing on upstream process development for biologics, with emphasis on mammalian cell culture, DoE and scale-up.

You will work across multidisciplinary teams, design experiments using QbD, operate Ambr systems and laboratory bioreactors, and contribute to data reporting, technology transfer and continuous