Technical Specialist – Bioanalysis & Biotransformation

Pharmaron; Rushden; In loco; GBP 60.000 - 85.000; Tempo pieno

Descrizione del lavoro

Pharmaron is seeking a Technical Specialist – Bioanalysis & Biotransformation in Rushden. You will lead metabolite identification and structure elucidation using high- resolution mass spectrometry, contribute to method development, and support global regulatory and non-regulatory studies.

You will work across in vitro, in vivo, clinical, biologics, and environmental fate projects, developing training and mentoring others while ensuring data integrity and client satisfaction.

Competenze

• PhD/MSc/BSc in Chemistry, Biochemistry, or related field.
• Experience in metabolite identification within CRO/pharma environment preferred.
• Strong chromatographic method development experience.
• Experience in GLP or regulated laboratory environments.
• Proficiency with HRMS platforms and data interpretation.

Mansioni

• Act as technical expert in metabolite identification and structure elucidation using HRMS.
• Conduct analytical/metabolite identification work for regulatory and non-regulatory studies per plan and timelines.
• Support studies across in vitro, in vivo, clinical, biologics, and environmental fate programmes.
• Develop and optimize LC-MS/MS chromatographic methods within the group.
• Interpret data and prepare study updates, documentation, and reports.
• Collaborate with Study Directors and Analytical Project Managers to ensure delivery.
• Contribute to client communications and discussions where appropriate.
• Develop training materials and deliver area-specific training.
• Mentor and support colleagues with best practices.
• Lead process improvement and new service development in area.
• Maintain equipment, software and lab areas.
• Address QA findings and audits; maintain SOPs as required.
• Contribute to external visibility via publications and presentations.

Conoscenze

Metabolite identification

Structure elucidation

LC-MS/MS data interpretation

Project management

Scientific reporting

Mentoring/coaching

Analytical method development

Good communication

Formazione

PhD/MSc/BSc in Chemistry or related

Strumenti

Waters Vion

Thermo Q Exactive

Xcalibur

Waters UNIFI

Compound Discoverer

Descrizione del lavoro

Job Introduction

Position: Technical Specialist – Bioanalysis & Biotransformation
Location: Rushden, UK

About Pharmaron

Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the UK, US, China, and Singapore, we support drug discovery through to manufacturing with fully integrated, high-quality services.

We're proud of the impact we make and just last year, we supported 887 discovery projects, 1,100+ CMC programs, and 1,397 clinical trials across all phases. Our teams are involved in everything from small molecules, ADCs, biologics, and gene therapies, and we work with more than 3,300 global customers. To learn more, visit www.pharmaron.com.

About The Role

We are seeking a Technical Specialist – Bioanalysis & Biotransformation to join our Metabolism team in Rushden. This is an exciting opportunity for an experienced scientist with strong expertise in high-resolution mass spectrometry, metabolite identification, structure elucidation, and LC-MS/MS data interpretation to play a key role in supporting global regulatory and non-regulatory studies.

Working as a technical specialist within the department, you will be responsible for conducting analytical and metabolite identification work across a range of study types, including in vitro, in vivo, clinical, large molecule/biological, and environmental fate studies. You will also contribute to method development, scientific reporting, client discussions, training, and continuous improvement initiatives within your specialist area.

Key Responsibilities

• Act as a technical expert in metabolite identification and structure elucidation using high-resolution mass spectrometry.
• Conduct analytical and metabolite identification work for regulatory and non-regulatory studies in line with study plans, analytical work plans, and project timelines.
• Support studies across in vitro, in vivo, clinical, large molecule/biological, and environmental fate programmes.
• Develop and optimise LC-MS/MS chromatographic methods within the group and across the wider Metabolism Department.
• Interpret analytical data and prepare accurate scientific updates, study documentation, and report contributions.
• Work closely with Study Directors and Analytical Project Managers to ensure successful delivery of client projects.
• Contribute scientifically to client communications and discussions, where appropriate.
• Develop training materials and deliver training in your area of specialism.
• Mentor and support colleagues by sharing technical knowledge and best practice.
• Lead process improvement and new service development projects within your specialist area.
• Maintain responsibility for assigned equipment, software, and laboratory areas.
• Address relevant findings arising from QA audits and process inspections.
• Maintain and write SOPs as required.
• Help raise the external profile of the department through publications, posters, presentations, and participation in expert groups.
• Ensure all work is performed in accordance with Health & Safety requirements, GxP standards, study plans, SOPs, and company procedures.

Candidate Profile

• PhD, MSc or BSc (Hons) in Chemistry, Biochemistry, or a related scientific discipline.
• Experience in metabolite identification within a CRO, pharmaceutical, or agrochemical environment would be highly desirable.
• Strong experience in chromatographic method development.
• Experience working within a GLP or regulated laboratory environment would be beneficial.
• Proficient in the use of high-resolution mass spectrometry platforms, such as Waters Vion or Thermo Q Exactive.
• Experience using relevant software packages such as Xcalibur, Waters UNIFI, and Compound Discoverer.
• Good knowledge of metabolism and metabolic reactions.
• Strong LC-MS/MS data interpretation and structure elucidation skills.
• Excellent scientific data interpretation, reporting, and presentation skills.
• Confident written and verbal communication skills, including the ability to present scientific findings to colleagues and clients.
• Strong organisational, problem-solving, prioritisation, and scheduling skills.
• Experience coaching, mentoring, or supporting the development of colleagues.
• Good project management skills.
• Proficient with Microsoft Office applications.
• Conscientious and meticulous approach to laboratory and written work.
• Ability to manage multiple priorities and work to tight deadlines in a fast-paced environment.
• Flexible, proactive, and willing to support changing study requirements, including occasional early starts, longer days, or weekend work where required.

Why Pharmaron?

Collaborative Culture: Thrive in an inclusive and innovative environment where teamwork and scientific excellence go hand in hand. At Pharmaron, our core values of “Employees First” and “Clients Centered” shape everything we do.

Meaningful Impact: Join a global organisation supporting world-leading pharmaceutical and biotechnology companies in the development of life-changing medicines.

Career Development: Work alongside industry experts, contribute to cutting-edge science, and benefit from excellent opportunities for professional growth within a truly global organisation.