Target Validation Scientist

CK Group; Slough; On-site; GBP 80,000 - 100,000; Full time

Job summary

A global biopharmaceutical company seeks a Target Validation Scientist in Slough on a contract basis. The role involves researching novel drug targets and requires expertise in immunology and various cellular techniques. Successful candidates will join a multi-disciplinary team to advance drug discovery efforts.

Qualifications

• Background in immunology or related field.
• Experience in cellular and molecular biology techniques required.
• Practical experience of bioinformatics and basic coding is advantageous.

Responsibilities

• Participate in the discovery and validation of novel drug targets.
• Study immunological disease pathways to identify therapeutic opportunities.
• Perform drug tractability and validation experiments.

Skills

Cell culture

Flow cytometry

High content imaging

Gene editing techniques

Bioinformatics

Education

BSc (or equivalent)

PhD/post-doc

Job description

CK Group are recruiting for a Target Validation Scientist, to join a global pharmaceutical company, on a contract basis, initially for 12 months, inside IR35.


Salary:

£20.68 - £35.00 per hour PAYE or £28.00 - £40.00 per hour Umbrella.


Target Validation Scientist Role:

• You will be part of a multi-disciplinary department, focusing on the discovery, validation, and mechanism of action of novel drug targets for diseases with high unmet patient need.
• Studying immunological disease pathways and biology, to generate novel insights into potential therapeutic opportunities in areas of unmet need.
• Setting up new and running new collaborations with state-of the-art researchers on auto-immune relevant biological pathways and disease models with the aim of identifying new disease-drug target links.
• Performing drug tractability and validation experiments, such as Gain of Function /Loss of Function assays, cell culture, flow cytometry, imaging, and other techniques.
• Produce detailed experimental write-ups and assist in producing and collating procedures, guidelines and reports.

Your Background:

• Background in immunology or related field.
• Experience in a range of cellular and molecular biology techniques – for example: cell culture, flow cytometry, high content imaging, IHC, ELISA or MSD, Western blotting, qPCR, transfection/siRNA/CRISPR gene-editing.
• Experience with use of bioinformatic tools to visualize and analyse large datasets.
• BSc (or equivalent) with more than 2 years of industry experience, or a PhD/post-doc.
• Practical experience of bioinformatic techniques and basic coding skills would be advantageous.

Company:

Our client is a global biopharmaceutical company, focused on creating value for people living with severe diseases in immunology and neurology, now and into the future.


Location:

This role is based at our client’s site in Slough.


Apply:

It is essential that applicants hold entitlement to work in the UK. Please quote job reference 138 956 in all correspondence.


Please note:

This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check.

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