Statistical Consultant

JR United Kingdom; Bolton; Remote; GBP 75,000 - 100,000; Full time

Job summary

A leading company is seeking a Statistical Science Associate Director to join their Statistical Innovation group. This role involves developing innovative statistical methodologies in clinical studies, supporting critical phases across diverse therapeutic areas, and collaborating with various disciplines to enhance drug development efficacy.

Qualifications

• Proven experience in academic research and/or clinical drug development.
• Research record supported by publications in top statistical journals.
• Understanding of clinical trial design and analysis.

Responsibilities

• Provide key input for solutions in the drug development cycle.
• Design early and late phase clinical studies, focusing on statistical methods.
• Lead strategic activities, improving clinical trial design and collaborating with external scientists.

Skills

Innovative statistical solutions

Collaborative working

Strong programming skills in R and/or SAS

Knowledge in safety data analysis

Knowledge of Bayesian methods

Education

PhD in Statistics or related discipline

Job description

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Statistical Consultant, Bolton, Greater Manchester

Location: Bolton, Greater Manchester, United Kingdom

Job Category: Other

EU work permit required: Yes

Job Views: 5

Posted: 04.06.2025

Expiry Date: 19.07.2025

Job Description:

Role: Statistical Science Associate Director – Statistical Innovation

Location: Remote

Duration: 12 months

Description

Do you have a passion for developing and aiding implementation of innovative statistical approaches and methods in clinical studies? Are you up for the challenge to impact a company that follows the science and turns ideas into life-changing medicines?

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide, while applying leading-edge approaches to science across many business areas. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to act, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.

We are recruiting a contractor to join our growing Statistical Innovation group as a Statistical Science Associate Director. Our main focus is providing statistical methodology support for all phases of clinical development for AZ’s Cardiovascular, Renal & Metabolism and Respiratory & Immunology divisions, along with specific support for Oncology, Rare Diseases, and Vaccine divisions.

In this role, you will belong to the Respiratory Biometrics and Statistical Innovation department, where our data-driven focus helps us work efficiently and creatively to bring the right medicines to the right patients. Our teams use their expertise in statistics and programming to address drug development objectives and reduce uncertainty in product development, driving better business decisions with quantitative reasoning.

Main duties and responsibilities

Joining a team of statistical methodology experts, you will provide key input to find solutions at critical stages in the drug development cycle. This work is technically challenging and dynamic. Your focus will be on producing pragmatic solutions within tight timeframes, prioritizing delivery before refinement.

You will contribute to or lead capability building in areas such as:

• Design of early and late phase clinical studies, including group sequential and adaptive designs using both frequentist and Bayesian approaches.
• Methods for analyzing real-time collected data, Estimands, Missing Data, Subgroup analyses, and Biomarkers.

You will also provide expert consultancy to other statisticians, medical scientists, and key roles across the business. This includes leading strategic activities like capability build projects, improving clinical trial design and analysis, developing new methodologies, and engaging with external scientists and regulators through publications, presentations, and collaborations. A proactive approach to identifying new areas where Statistical Innovation can add value is also expected, along with developing relationships with external scientific and academic communities.

Requirements:

• PhD in Statistics or a related discipline, with experience in academic research and/or clinical drug development.
• Proven ability to deliver innovative statistical solutions, including design of clinical studies, analysis of real-time data, handling missing data, estimands, subgroups, and biomarkers.
• Strong programming skills in R and/or SAS.
• High competence in collaborative working across disciplines and geographies.
• Research record supported by publications in top statistical journals.
• A desire to apply scientific expertise to practical problems benefiting patients.
• Knowledge or research experience in safety data analysis, observational studies, meta-analysis, Bayesian methods, nonlinear, and mixed-effect models.
• Awareness of evolving scientific and regulatory statistical issues.