Sr Clinical Trial Manager

JR United Kingdom; Stoke-on-Trent; On-site; GBP 55,000 - 75,000; Full time

Job summary

A leading oncology-focused midsized pharma company is seeking a Senior Clinical Trial Manager in Stoke-on-Trent to oversee early-phase oncology programs. The successful candidate will manage clinical trials, ensuring compliance with protocols and regulations, while working cross-functionally and fostering relationships with trial sites and investigators.

Qualifications

• Minimum 5 years of clinical operational experience in biotech, pharma, or CROs.
• Strong understanding of GCP, ICH, GDP, CFRs; familiarity with MHRA, EMA, and international regulations is a plus.
• Knowledge and experience in oncology.

Responsibilities

• Oversee clinical trial sites from start-up to close-out, ensuring compliance.
• Collaborate with Clinical Project Manager, CROs, and vendors.
• Develop patient recruitment and retention strategies.

Skills

Communication

Problem-Solving

Job description

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Sr Clinical Trial Manager, Stoke-on-Trent

Client: Advanced Clinical

Location: Stoke-on-Trent, United Kingdom

Job Category: Other

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EU work permit required: Yes

Job Views: 4

Posted: 06.06.2025

Expiry Date: 21.07.2025

Job Description:

Senior Clinical Trial Manager (via FSP)

Oncology-Focused Midsized Pharma Company - Early Phase

This role will focus on the Early Phase Oncology program in the UK and mainland Europe. Candidates must have recent experience with early-phase oncology studies at a CRO, biotech, or pharmaceutical company.

Responsibilities:

• Oversee clinical trial sites from start-up to close-out, ensuring compliance with protocols, ICH guidelines, GCP, and regulations.
• Collaborate with Clinical Project Manager, CROs, and vendors to manage studies effectively.
• Supervise Clinical Trial Managers to meet deliverables on time, within budget, and to quality standards.
• Participate in planning, implementing, and managing clinical trials in compliance with regulations.
• Oversee CROs and sites, ensuring timely delivery and high-quality data.
• Monitor site visit metrics, data quality, and protocol deviations; conduct oversight visits.
• Assist in site initiation visits and foster relationships among sponsors, CROs, and investigators.
• Review monitoring reports and escalate issues as needed.
• Coordinate study start-up activities, including contract negotiations and documentation.
• Ensure consistency in Clinical Operations processes across trials and regions.
• Work cross-functionally to meet study requirements and timelines.
• Develop and review study documents and train staff.
• Monitor action items and data trends, addressing issues with CROs.
• Develop patient recruitment and retention strategies.

Experience:

• Minimum 5 years of clinical operational experience in biotech, pharma, or CROs.
• Strong understanding of GCP, ICH, GDP, CFRs; familiarity with MHRA, EMA, and international regulations is a plus.
• Experience with site start-up and initiation.
• Ability to build relationships with trial sites and investigators.
• Strong communication skills.
• Proactive problem-solving skills.
• Ability to work independently and present effectively.
• Knowledge and experience in oncology.
• Previous CRA experience preferred.