Sr Biostatistician (Early Phase)

Syneos Health, Inc.; United Kingdom; Remote; GBP 60,000 - 100,000; Full time

Job summary

Join a leading biopharmaceutical solutions organization that is dedicated to accelerating customer success and improving patient lives. As a Sr. Principal Biostatistician, you'll leverage your expertise in statistical design and clinical trials to lead multiple studies and mentor a team of biostatisticians. This role offers the opportunity to work in a dynamic environment where your contributions will directly impact the success of innovative therapies. Collaborate with passionate problem solvers and be part of a culture that values diversity, growth, and authentic self-expression. If you're looking to make a difference in the healthcare landscape, this is the role for you.

Benefits

Career Growth Opportunities

Supportive Management

Training and Development

Peer Recognition Programs

Diversity and Inclusion Initiatives

Qualifications

• Graduate degree in biostatistics or related field required.
• Extensive experience in clinical trials and statistical analysis.
• Proficiency in programming and regulatory submission experience preferred.

Responsibilities

• Mentor biostatisticians and oversee project activities.
• Prepare Statistical Analysis Plans and ensure data quality.
• Manage multiple projects and communicate timelines effectively.

Skills

Statistical Design

Clinical Trials Management

Statistical Programming

Communication Skills

Education

Graduate degree in Biostatistics

Tools

SAS

R

Job description

Updated: April 27, 2025
Location: United Kingdom-Europe - GBR-Home-Based, United Kingdom
Job ID:25001937

* Must be located in UK, Ireland, Poland, Spain, Greece, Hungary, Romania, Ukraine, South Africa, Argentina, Mexico, Brazil, or Colombia to be considered for this role.

Sr- Principal Biostatistician (Previous Experience with Early Phase is required)

Syneos Health is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate clinical, medical affairs, and commercial insights into outcomes to address modern market realities.

Our Clinical Development model centers on the patient and the customer. We continuously seek to simplify and streamline our work to make Syneos Health a better place to work and collaborate.

Whether in a Functional Service Provider partnership or a Full-Service environment, you'll work with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate therapy delivery because we are passionate about changing lives.

Discover what our 29,000 employees across 110 countries already know:
WORK HERE MATTERS EVERYWHERE

Why Syneos Health

• We are passionate about developing our people through career growth, supportive management, training, peer recognition, and rewards.
• We foster a Total Self culture—where you can be authentic. We are dedicated to caring for our people.
• We value diversity of thought, background, and culture, creating a sense of belonging for all.

Job Responsibilities

1. Serve as a statistical department resource, mentor biostatisticians, and develop training materials. Conduct training sessions and support skill development.
2. Oversee activities of biostatistics personnel on projects, ensuring high-quality, timely work. Provide independent review of project outputs.
3. Support all statistical tasks throughout the project lifecycle, from protocol to CSR.
4. Prepare or oversee Statistical Analysis Plans (SAPs), including mock-up displays for tables, listings, and figures. Collaborate with sponsors as needed.
5. Lead as Biostatistician for protocol aspects, randomization schedules, and input to clinical study reports.
6. Create or review programming specifications for analysis datasets, tables, listings, and figures.
7. Review CRFs, database design, and documentation to ensure protocol compliance and data quality.
8. Implement company objectives and develop solutions for business challenges.
9. Represent biostatistics on project teams, interfacing with other departments.
10. Prepare for meetings, contribute ideas, and respect others' opinions.
11. Verify and quality control project deliverables, ensuring they meet standards and specifications.
12. Manage multiple projects, set goals, and communicate timelines and challenges proactively.
13. Monitor progress against milestones and escalate issues as needed.
14. Provide statistical programming support as required.
15. Participate in DSMB/DMC activities, possibly serving as a voting statistician.
16. Follow SOPs, WIs, and regulatory guidelines (e.g., ICH).
17. Maintain organized project documentation and verification files.
18. Collaborate with others and support business development activities.
19. Perform additional duties as assigned; minimal travel may be required.

Qualifications

What we’re looking for

• Graduate degree in biostatistics or related field.
• Extensive experience in clinical trials, capable of leading multiple studies.
• Proficiency in programming.
• Deep knowledge of statistical design, analysis, regulatory guidelines, and programming techniques.
• Experience supporting all statistical tasks in clinical trials lifecycle.
• Regulatory submission experience preferred.
• Excellent communication skills in English.

Get to know Syneos Health

Over the past 5 years, we’ve worked with 94% of all FDA-approved drugs, 95% of EMA products, and conducted over 200 studies with 73,000 sites and 675,000 patients.

Join us to challenge the status quo in a dynamic environment. Learn more about Syneos Health.

Additional Information

Tasks and responsibilities are not exhaustive. The company may assign other duties at its discretion. Equivalent experience, skills, and education will be considered. This does not constitute a contract. We comply with all applicable legislation and promote diversity, equity, and inclusion. We are committed to providing reasonable accommodations under the ADA.

Our 29,000+ employees know: work here matters everywhere. We aim to improve patients' lives worldwide through our work. A career with Syneos Health guarantees meaningful work and professional growth.