Senior Strain Engineer – Microbial Engineering & DNA Design

flagshippioneeringinc; Cambridge; On-site; GBP 78,000 - 107,000; Full time

Job summary

Flagship Pioneering in Cambridge, MA, is seeking a Senior Research Associate to support genetic engineering of microbial strains for recombinant protein production. Reporting to the Senior Scientist, you will work hands-on in a fast-paced startup environment, designing and assembling DNA and evaluating strain performance.

The role demands practical experience with DNA assembly strategies, microbial culture, and robust laboratory operations, with collaboration across discovery, bioprocess

Qualifications

• Bachelor's or Master's in Bioengineering, Biochemistry, Microbiology, Biotechnology or related field.
• Hands-on molecular biology design, isolation and DNA assembly.
• Strong aseptic technique and microbial culture handling.
• Excellent communication, organization and documentation skills.

Responsibilities

• Construct plasmids using Golden Gate or HiFi assembly.
• Prepare competent cells and perform PCR for genetic engineering.
• Conduct gel electrophoresis, nucleic acid quantification, and sample prep.
• Track strain performance and coordinate with discovery and analytical teams.
• Maintain plasmid banks, media, and experimental records.

Skills

DNA assembly

PCR techniques

Aseptic technique

Microbial culture handling

Communication & documentation

Education

Bachelor's degree in related field

Master's degree in related field

Tools

Benchling

Geneious

NGS analysis

Job description

Flagship Pioneering in Cambridge, MA, is seeking a Senior Research Associate to support genetic engineering of microbial strains for recombinant protein production. Reporting to the Senior Scientist, you will work hands-on in a fast-paced startup environment, designing and assembling DNA and evaluating strain performance.

The role demands practical experience with DNA assembly strategies, microbial culture, and robust laboratory operations, with collaboration across discovery, bioprocess