Senior Statistical Programmer

JR United Kingdom; High Wycombe; Remote; GBP 50,000 - 70,000; Full time

Job summary

A leading global CRO is seeking Senior and Principal Statistical Programmers for an impactful role in High Wycombe. The position requires robust programming expertise across various therapeutic areas and involves activities such as programming SDTMs and ADaMs, as well as producing TFLs. The ideal candidate will be proactive, with strong communication skills and a solid educational background in a relevant field. This opportunity offers competitive remuneration and a flexible work environment.

Benefits

Structured training and development plans

Condensed hours for a shorter workweek

Competitive salary and benefits package

Fully remote role available

Qualifications

• Experience in producing high-quality TFLs for internal projects.
• Hands-on experience with Disclosure Tables, especially Basic Results tables.
• Strong understanding of clinical data flow from raw datasets.

Responsibilities

• Program and validate SDTMs, ADaMs, and complex efficacy/lab datasets.
• Lead programming activities, ensuring timely, high-quality deliverables.
• Collaborate with statisticians and PMs on resourcing and planning.

Skills

Programming expertise

Data analysis

Leadership

Problem-solving

Communication

Education

BSc, MSc, or PhD in Mathematics, Science, or IT-related field

Tools

SAS

R

Python

Job description

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Senior Statistical Programmer, high wycombe

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Client:

Warman O'Brien

Location:

high wycombe, United Kingdom

Job Category:

Other

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EU work permit required:

Yes

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Job Views:

15

Posted:

06.06.2025

Expiry Date:

21.07.2025

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Job Description:

Senior / Principal Statistical Programmers | Global CRO | UK | France | Poland | Spain |

We are partnering with a market-leading global CRO to recruit a Senior and/or Principal Statistical Programmer for a dynamic and high-impact role. This is not a traditional programming position, we’re looking for an experienced professional with robust, end-to-end programming expertise across multiple therapeutic areas.

The ideal candidate will have a strong background in data anonymization and disclosure, with hands-on experience in producing high-quality TFLs for internal projects. Expertise in generating Disclosure Tables, particularly Basic Results tables, is essential. Versatility, flexibility, and a proactive approach to working across diverse therapeutic areas will be key to success in this role.

What you will be doing:

• Program and validate SDTMs, ADaMs, and complex efficacy/lab datasets.
• Proficient in SAS (Base, Macros, Graphs); experience with R or Python is advantageous.
• Must have hands-on experience with Disclosure tables, especially Basic Results tables.
• Develop/debug complex macros and program non-efficacy outputs/figures.
• Strong understanding of clinical data flow from raw datasets to submission-ready formats.
• Skilled in TFL production programming for internal studies.
• Create, QC, and update complex dataset specs across single/multiple studies.
• Interpret and apply current SDTM, ADaM, and FDA CRT standards (define.xml/.pdf).
• Independently review SAPs and shells; contribute feedback.
• Adhere to SOPs, study documentation, and internal quality standards.
• Lead programming activities, ensuring timely, high-quality deliverables.
• Collaborate with statisticians and PMs on resourcing and planning.
• Act as programming point of contact; ensure cohesive team performance.
• Promote best practices and support internal training initiatives.

What you will need:

• BSc, MSc, or PhD in Mathematics, Science, or IT-related field.
• Strong written, verbal, and interpersonal communication skills.
• Proactive, innovative mindset with a willingness to challenge the status quo.
• Effective at prioritization, time management, and project delivery.
• Collaborative team player with cross-functional experience.
• Strong leadership, problem-solving, and decision-making abilities.
• Be available on a short notice period.

What’s in it for you:

• Recognized as an outstanding workplace, committed to employee engagement, satisfaction, and work-life balance.
• Structured training, development plans, and a supportive, friendly environment.
• Condensed hours for a shorter workweek.
• Competitive salary and benefits package.
• Fully remote role available in the UK, France, Spain, or Poland.

What to do next:

If this opportunity is of interest, please apply now with your CV as the organisation are looking to welcome the Senior & Principal Statistical Programmers onboard as soon as possible.

Not what you’re looking for?

Please contact Jo Fornaciari on [phone] for a confidential discussion about potential opportunities.