Senior Statistical Programmer

JR United Kingdom; Derby; Remote; GBP 50,000 - 80,000; Full time

Job summary

A global CRO is seeking a Senior / Principal Statistical Programmer for a pivotal role in statistical programming across various therapeutic areas. This position requires a broad skill set in data handling, programming, and collaboration with clinical teams, providing a dynamic opportunity for professional growth in a supportive environment. Competitive salary and remote work options are available for qualified candidates.

Benefits

Structured training and development plans

Competitive salary and benefits package

Condensed hours for a shorter workweek

Recognized as an outstanding workplace

Supportive, friendly environment

Qualifications

• Strong written, verbal, and interpersonal communication skills.
• Proactive, innovative mindset with a willingness to challenge the status quo.
• Strong leadership, problem-solving, and decision-making abilities.

Responsibilities

• Program and validate SDTMs, ADaMs, and complex datasets.
• Independently review SAPs and shells; contribute feedback.
• Lead programming activities, ensuring timely, high-quality deliverables.

Skills

Programming expertise

Data anonymization

Statistical programming

Collaboration

Problem-solving

Education

BSc, MSc, or PhD in Mathematics, Science, or IT-related field

Tools

SAS

R

Python

Job description

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Senior / Principal Statistical Programmers | Global CRO | UK | France | Poland | Spain |

We are partnering with a market-leading global CRO to recruit a Senior and/or Principal Statistical Programmer for a dynamic and high-impact role. This is not a traditional programming position, we’re looking for an experienced professional with robust, end-to-end programming expertise across multiple therapeutic areas.

The ideal candidate will have a strong background in data anonymization and disclosure, with hands-on experience in producing high-quality TFLs for internal projects. Expertise in generating Disclosure Tables, particularly Basic Results tables, is essential. Versatility, flexibility, and a proactive approach to working across diverse therapeutic areas will be key to success in this role.

What you will be doing:

• Program and validate SDTMs, ADaMs, and complex efficacy/lab datasets.
• Proficient in SAS (Base, Macros, Graphs); experience with R or Python is advantageous.
• Must have hands-on experience with Disclosure tables, especially Basic Results tables.
• Develop/debug complex macros and program non-efficacy outputs/figures.
• Strong understanding of clinical data flow from raw datasets to submission-ready formats.
• Skilled in TFL production programming for internal studies.
• Create, QC, and update complex dataset specs across single/multiple studies.
• Interpret and apply current SDTM, ADaM, and FDA CRT standards (define.xml/.pdf).
• Independently review SAPs and shells; contribute feedback.
• Adhere to SOPs, study documentation, and internal quality standards.
• Lead programming activities, ensuring timely, high-quality deliverables.
• Collaborate with statisticians and PMs on resourcing and planning.
• Act as programming point of contact; ensure cohesive team performance.
• Promote best practices and support internal training initiatives.

What you will need:

• BSc, MSc, or PhD in Mathematics, Science, or IT-related field.
• Strong written, verbal, and interpersonal communication skills.
• Proactive, innovative mindset with a willingness to challenge the status quo.
• Effective at prioritization, time management, and project delivery.
• Collaborative team player with cross-functional experience.
• Strong leadership, problem-solving, and decision-making abilities.
• Be available on a short notice period.

What’s in it for you:

• Recognized as an outstanding workplace, committed to employee engagement, satisfaction, and work-life balance.
• Structured training, development plans, and a supportive, friendly environment.
• Condensed hours for a shorter workweek.
• Competitive salary and benefits package.
• Fully remote role available in the UK, France, Spain, or Poland.

What to do next:

If this opportunity is of interest, please apply now with your CV as the organisation are looking to welcome the Senior & Principal Statistical Programmers onboard as soon as possible.

Not what you’re looking for?

Please contact Jo Fornaciari on [phone] for a confidential discussion about potential opportunities.