Senior Scientist (SS), Antibody and Discovery Engineering

ONE NUCLEUS; Cambridge; On-site; GBP 50,000 - 70,000; Full time

Job summary

A leading company in biopharmaceuticals is seeking a highly capable Senior Scientist for their Discovery & Engineering Unit in Cambridge. In this lab-based role, you will drive antibody-based therapeutics projects, collaborate with experts, and lead cutting-edge research directions. The ideal candidate will possess extensive experience in antibody drug discovery and excellent leadership skills, contributing to high-impact scientific advancements.

Qualifications

• 6+ years of experience in antibody drug discovery.
• Hands-on experience with phage/mammalian display.
• Experience in project and line management is desirable.

Responsibilities

• Lead antibody discovery programs with high-quality outcomes.
• Manage client and stakeholder relationships for project success.
• Design and execute experiments while communicating findings.

Skills

Antibody Discovery

Molecular Biology

Biotechnology

Flow Cytometry

Data Analysis

Problem-Solving

Education

PhD in Antibody Discovery, Molecular Biology, Biotechnology, or related field

Tools

Antibody Display Technologies

Biochemical Assays

DNA Cloning

Job description

The Role
We are seeking a highly capable and enthusiastic Senior Scientist to join the expanding Discovery & Engineering Unit at our South Cambridgeshire site (DEU III). Teamwork is a key skill for this role - Senior Scientists are the highest-level lab-based role in FairJourney Biologics, providing lab-based leadership and collaborating with internal experts in antibody discovery & display technologies.

You will use your keen interest and expertise in Biologics drug discovery to shape and deliver projects involving identification, optimisation and screening of novel antibody-based therapeutics, applying and refining our (phage and mammalian) display technologies and engineering methods. This will be an onsite and predominantly lab-based role, reporting to a team leader.

Your responsibilities will include the independent design and execution of experiments, data analysis and interpretation and communication of the findings to the team and clients. A positive and solution focused mindset is required to deliver on a wide range of innovative and intellectually challenging projects.

Key responsibilities
-Lead antibody discovery programs using phage and/or mammalian display, ensuring timely delivery and high-quality outcomes.
-Manage and strengthen client and internal stakeholder relationships to drive project success.
-Apply your knowledge of antibody drug discovery to shape and guide project decisions in collaboration with team leaders and clients.
-Initiate and lead novel research directions and strategic initiatives to advance business objectives.
-Work with the Technology Unit to evaluate and integrate novel platforms to the drug discovery process. As a line manager, support individuals to deliver project work and develop professionally.
-Collect, analyse, and interpret scientific data to inform decision-making.
-Present findings and progress updates to senior management, partners, and at scientific conferences.

Your Profile
-PhD (or equivalent industry experience) in Antibody Discovery, Molecular Biology, Biotechnology, Immunology, or a related field.
-6+ years of hands-on experience in antibody drug discovery, preferably within industry, with a demonstrable understanding of therapeutic antibody formats, structures and sequences.
-Practical experience in antibody display technologies (e.g. phage/mammalian display)
-Experience in antibody display library construction would be an advantage.
-In-depth understanding and practical research experience of molecular biology and cellular biology techniques, including DNA cloning and mammalian cell culture.
-Experience of antibody isolation and engineering for optimisation.
-Hands-on experience with flow cytometry & FACS.
-Demonstrable experience in in vitro cell-based assays (e.g. reporter,TDCC).
-Experience in biochemical assays, (e.g. ELISA, SPR).
-Excellent data analysis, interpretation and problem-solving skills.
-Influencing skills to shape project decisions and direction.
-Ability to plan time and prioritise work.
-Maintain clear written records in a timely manner.
-The ability to present and communicate effectively to internal and external stakeholders.
-Prior experience in project and line management is desirable.