Senior Scientist, Spatial Omics & Tissue Biology

UCB; Slough; Hybrid; GBP 55,000 - 85,000; Full time

Job summary

UCB is seeking a Scientist or Senior Scientist to join the UK Research team in Slough, moving to Windlesham in 2027. The role blends wet-lab and computational work to advance spatial biology and spatial omics for immune memory targets.

You will design end-to-end spatial omics studies, generate data across platforms, and collaborate with histology and bioinformatics teams to translate findings into development programs.

Qualifications

• BSc, MSc, or PhD in a life-science or computational discipline.
• 2–3 years hands-on experience generating and analysing spatial omics data.
• Practical experience with spatial transcriptomics and histology-based methods.
• Strong computational skills for spatial data analysis (Python/sc-verse preferred; R valued).
• Experience with image analysis and platforms such as QuPath, Visiopharm, or OMERO.
• Familiarity with Git, version control, and scalable data workflows.

Responsibilities

• Design and deliver spatial omics experiments and analyses aligned to project objectives.
• Generate spatial transcriptomic data using platforms such as Visium HD, Xenium/CosMX, GeoMX, and complementary methods including RNAscope, IHC/IF, and H&E.
• Perform histology activities including tissue processing, sectioning, staining, antigen retrieval, and reagent optimisation.
• Analyse spatial transcriptomics and imaging data using computational and visualisation tools.
• Integrate spatial data into broader tissue-profiling pipelines to support disease understanding and decision-making.
• Communicate findings clearly through reports, visualisation platforms, and cross-functional presentations.
• Maintain high standards of documentation, compliance, and data integrity using electronic lab notebooks.
• Contribute to publications, patents, and scientific dissemination where appropriate.
• Support the evolution of UCB’s spatial biology capabilities by staying current with emerging technologies and literature.
• Mentor and support colleagues, depending on experience level.
• Ensure compliance with HTA, Health & Safety, and regulatory requirements when working with human tissue.

Skills

Spatial omics

Spatial transcriptomics

Histology methods

Python

Image analysis

QuPath

Git

Education

BSc/MSc/PhD in life sciences or computational field

Tools

Visium HD

Xenium CosMX

GeoMX

RNAscope

IHC/IF

Job description

UCB is seeking a Scientist or Senior Scientist to join the UK Research team in Slough, moving to Windlesham in 2027. The role blends wet-lab and computational work to advance spatial biology and spatial omics for immune memory targets.

You will design end-to-end spatial omics studies, generate data across platforms, and collaborate with histology and bioinformatics teams to translate findings into development programs.