Senior Scientist - qPCR Assay Verification

Origin Sciences; Cambridge; On-site; GBP 50,000 - 75,000; Full time

Benefits offered by this job

25 days leave

Pension

Competitive salary

Wellbeing program

Job summary

Origin Sciences, based at Granta Park, Cambridge, seeks an Assay Verification Scientist to lead verification across qPCR assays in a confidential molecular diagnostics programme. You will design, execute and report verification studies, ensuring robust evidence for transfer to internal or external labs and compliance with quality requirements.

Reporting to the Director of Innovation, you will collaborate with Quality, Regulatory, Clinical, Operations and suppliers to drive assay verification,

Qualifications

• MSc or PhD in molecular biology, biomedical science or related discipline.
• Advanced qPCR expertise with assay development, verification and validation.
• Experience across at least two major qPCR platforms and cross-platform transfer.

Responsibilities

• Plan, execute, analyse and report verification and validation studies (pre-analytics, nucleic-acid extraction, qPCR, controls).
• Develop and transfer qPCR assays across platforms; define criteria and evidence of performance.
• Evaluate LOD, precision, accuracy, reproducibility and robustness; manage variability.
• Define run validity and containment of contamination; escalate when data integrity is at risk.
• Produce clear protocols, reports, SOPs with traceability and CAPA.

Skills

qPCR expertise

Multi-platform qPCR

Data interpretation

Communication

Laboratory readiness

Education

MSc or PhD in molecular biology/biomedical sciences

Tools

QuantStudio

LightCycler

Bio-Rad CFX

LIMS

Job description

Origin Sciences, based at Granta Park, Cambridge, seeks an Assay Verification Scientist to lead verification across qPCR assays in a confidential molecular diagnostics programme. You will design, execute and report verification studies, ensuring robust evidence for transfer to internal or external labs and compliance with quality requirements.

Reporting to the Director of Innovation, you will collaborate with Quality, Regulatory, Clinical, Operations and suppliers to drive assay verification,