Senior Scientist: Molecular Diagnostics for CRC Screening

Origin Sciences; Cambridge; On-site; GBP 65,000 - 90,000; Full time

Benefits offered by this job

25 days holidays

Pension contribution

Competitive Salary

Job summary

Origin Sciences is seeking a Senior Scientist with expertise in molecular diagnostics, biomarker validation, PCR-based assays and NGS, to lead and support laboratory processes within the Production Team, focusing on molecular biology and NGS technologies.

You will operate, optimize and maintain validated workflows, transfer methods to routine use, contribute to documentation for regulatory submissions, and collaborate cross‑functionally to ensure quality, data integrity and timely results.

Qualifications

• Enthusiastic and self-motivated individual.
• MSc/PhD in Genetics, Epigenetics, Cancer Biology, Molecular Biology or Biochemistry
• Greater than 3 years of scientific research experience in next-generation sequencing and assay development
• Excellent understanding of molecular biology techniques
• Excellent attention to detail and record keeping
• Ability to critically evaluate data, focusing on quality and reproducibility
• Proficiency in time management, multitasking, and the ability to collaborate with a multidisciplinary team
• Good organisational skills
• Strong interpersonal communication skills

Responsibilities

• Perform nucleic acid extraction and store biobank clinical samples
• Support the implementation and verification of new and updated detection workflows
• Liaise with the clinical trial teams to coordinate clinical sample deliveries
• Complete stability, performance, and validation assays, followed by analysis and reporting
• Execute and maintain established assays for routine sample testing
• Work towards the goals of collaborative projects with external partners
• Be accountable for the time, cost, and quality of agreed deliverables
• Provide updates on the progress, risks, and opportunities of the agreed deliverables
• Work within a regulated environment in accordance with ISO 13485 and ISO 15189
• Assess related diagnostic technologies and products
• Contribute to scientific communication and documentation, including peer-reviewed publications, leaflets and posters, as required
• Support the day-to-day management of laboratory pipelines and workflows, including sample tracking, scheduling, and throughput monitoring, to ensure the timely and reproducible delivery of results
• To ensure projects are carried out in accordance with Origin's Quality Systems and Regulatory Standards

Skills

NGS

PCR

Molecular biology

Biomarker validation

Assay development

Data analysis

Team collaboration

Attention to detail

Education

MSc/PhD in Genetics, Epigenetics, Cancer Biology, Molecular Biology or Biochemistry

Tools

NGS platforms

PCR techniques

Job description

Origin Sciences is seeking a Senior Scientist with expertise in molecular diagnostics, biomarker validation, PCR-based assays and NGS, to lead and support laboratory processes within the Production Team, focusing on molecular biology and NGS technologies.

You will operate, optimize and maintain validated workflows, transfer methods to routine use, contribute to documentation for regulatory submissions, and collaborate cross‑functionally to ensure quality, data integrity and timely results.