Senior / Scientist - Project Biology – Target Validation

Relation; London; On-site; GBP 40,000 - 55,000; Full time

Job summary

Relation, a leading biotech company in London, seeks a Senior Scientist for Project Biology to advance drug discovery initiatives. The role involves executing target validation experiments and collaborating with interdisciplinary teams to drive innovative therapies. Ideal candidates will have a PhD and experience in cellular biology and assay development.

Qualifications

• PhD with experience in assay development and/or target validation.
• Experience with mammalian cellular models and functional disease relevant endpoints.
• Knowledge of gene editing tools and RNA interference.

Responsibilities

• Contribute to projects focused on understanding novel target biology.
• Maintain cell lines and utilize CRISPR/Cas9 for experiments.
• Generate and analyze biological data for drug discovery projects.

Skills

Cellular and molecular biology

Assay development

Target validation

CRISPR/Cas9 gene editing

Flow cytometry

Fluorescence microscopy

RT-qPCR

Education

PhD

Job description

Senior / Scientist - Project Biology – Target Validation

Join to apply for the Senior / Scientist - Project Biology – Target Validation role at Relation

Senior / Scientist - Project Biology – Target Validation

Join to apply for the Senior / Scientist - Project Biology – Target Validation role at Relation

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About Relation

Relation is an end-to-end biotech developing transformational medicines, with technology at our core. Our ambition is to understand human biology in unprecedented ways, discovering therapies to treat some of life’s most devastating diseases. We leverage single-cell multi-omics directly from patient tissue, functional assays, and machine learning to drive disease understanding, from cause to cure.

London

About Relation

Relation is an end-to-end biotech developing transformational medicines, with technology at our core. Our ambition is to understand human biology in unprecedented ways, discovering therapies to treat some of life’s most devastating diseases. We leverage single-cell multi-omics directly from patient tissue, functional assays, and machine learning to drive disease understanding, from cause to cure.

This year, we’ve embarked on an exciting double collaboration with GSK to tackle fibrosis and osteoarthritis, alongside advancing our own internal osteoporosis programme. By combining our cutting-edge ML capabilities with their deep expertise in drug discovery, this partnership underscores our commitment to pioneering science and delivering impactful therapies to patients.

We are rapidly scaling our technology and discovery teams, offering a unique opportunity to join one of the most innovative Biotech companies. Be part of our dynamic, interdisciplinary teams, collaborating closely to redefine the boundaries of possibility in drug discovery. Our state-of-the-art wet and dry laboratories, located in the heart of London, provide an exceptional environment to foster interdisciplinarity and turn groundbreaking ideas into positive impact for patients.

We are committed to building diverse and inclusive teams. Relation is an equal opportunities employer and does not discriminate on the grounds of gender, sexual orientation, marital or civil partner status, gender reassignment, race, colour, nationality, ethnic or national origin, religion or belief, disability, or age. We cultivate innovation through collaboration, empowering every team member to do their best work and develop to their highest potential.

By joining Relation, you will be part of an exceptionally talented team, with extraordinary leverage to advance the field of drug discovery. Your work will shape our culture, strategic direction, and, most importantly, impact patients’ lives.

Opportunity

We have an exciting opportunity for a Senior Scientist or Scientist - Project Biology, to join Relation’s cutting-edge experimental laboratory and contribute to our drug discovery initiatives. The successful candidate will be supporting and executing mechanistic target validation experiments, generating and interpreting scientific data, and supporting the maintenance of the laboratory. Your contributions will be part of advancing our research and ensuring successful project outcomes.

As part of the Relation team, you will join a team of talented professionals, including wet-lab scientists and data scientists and gain exposure to a diverse range of skills, both in and outside of your primary area of expertise. You will have the opportunity to contribute to the development of our positive and inclusive organisational culture and ultimately, make a positive impact on patients' lives.

Your Responsibilities

• Scientist proficient in cellular and molecular biology to contribute to projects focussed on understanding novel target biology
• Contribute to orthogonal validation projects by maintenance of cell lines, utilisation of CRISPR/Cas9 gene editing & microscopy endpoints
• Generate, analyse & contribute biological data to Relations novel drug discovery projects.
• Working as a member of the lab team to ensure efficient running of the lab, including a variety of responsibilities as required.
  
  

Professionally, you have

• A PhD with experience in assay development and/or target validation.
• Experience with a variety of mammalian cellular models including established cell lines, patient-derived primary cells with functional disease relevant endpoints with the aim of ensuring required reproducibility and sensitivity in those assays.
• Experience using multi-parameter endpoints including, but not limited to flow cytometry, fluorescence microscopy, plate based fluorescent assays, soluble ligand analysis, RT-qPCR.
• Knowledge of gene editing tools (e.g., CRISPR/Cas9) and RNA interference for modulating gene expression cell systems.
• A proven ability to work closely within cross-functional teams to progress target validation projects and present findings to internal stakeholders.
  
  

Desirable Knowledge Or Experiences

• Comfortable working in a Biotech environment, previous Pharma or Biotech experience is desirable.
• An ability to multitask and effectively contribute to multiple projects in parallel in response to changing priorities.
  
  

Personally, you are

• A collaborative team player.
• A clear and effective communicator.
• Driven by the impact of preclinical development
• Motivated to stay at the forefront of scientific advancements.
• Passionate about contributing to meaningful advancements in healthcare.
  
  

Join us in this exciting role where your contributions will have a direct impact on advancing our understanding of genetics and disease risk, supporting our mission to get transformative medicines to patients. Together, we're not just doing research; we're setting new standards in the field of machine learning and genetics. The patient is waiting!

Relation is a committed equal opportunities employer.

RECRUITMENT AGENCIES: Please note that Relation does not accept unsolicited resumes from agencies. Resumes should not be forwarded to our job aliases or employees. Relation Therapeutics will not be liable for any fees associated with unsolicited CVs.

Seniority level

• Seniority level

  Not Applicable

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

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