Senior Scientist II - LCMS/MS

Synexa Life Sciences; Macclesfield; On-site; GBP 40,000 - 60,000; Full time

Job summary

A leading life sciences organization in Macclesfield is looking for a Senior Scientist II to lead laboratory studies and drive the development of bioanalytical assays. The role involves ensuring compliance with regulatory standards while managing projects, mentoring teams, and collaborating with clients. Strong experience in analytical techniques and a Master's degree in a relevant field are required.

Qualifications

• Strong knowledge of analytical techniques and hands-on experience with LC/MS.
• Proficient in following protocols and using standard equipment.
• Good command of written and spoken English.

Responsibilities

• Lead laboratory studies and ensure compliance with GxP guidelines.
• Develop and validate bioanalytical assays for clinical studies.
• Draft and review project documents ensuring high-quality reporting.

Skills

Analytical techniques

LC/MS experience

Collaboration skills

Negotiation skills

Education

Master's degree in natural science

Tools

Mass Spectrometry

Centrifuges

Biosafety cabinets

Incubators

Job description

Overview

As a Senior Scientist II, you'll lead laboratory studies, drive the development and validation of bioanalytical and immunological assays, and ensure compliance with GxP and global regulatory standards. You\'ll manage projects end-to-end, mentor teams, and partner with clients while shaping innovative solutions in a dynamic scientific environment.

Main Areas of Responsibility

• Lead study specific laboratory staff and ensure compliance with GxP and latest guidelines.
• Develop, validate, and apply bioanalytical and immunological assays for pre-clinical, clinical studies, and drug batch characterization as Responsible Scientist (RS), Study Director (SD) or Principal Investigator (PI).
• Study specific consultation, capacity management, reagent planning, inventory, troubleshooting, and training.
• Conduct and manage sample analysis, validation and method development studies.
• Draft and review project documents (e.g., lab manuals, validation plans, sample analysis reports), ensuring high-quality reporting and client communication.
• Lead studies, manage pre- and post-contract phases (change order management, reagent plans, protocols, quotes), and support revenue generation.
• Maintain ERP timesheets and unit logging, provide training, and contribute to achieving monthly revenue targets.
• Stay updated on bioanalysis trends, continuous GxP-related training, implement EMA/FDA guidelines, assess systems for improvements, and share knowledge regularly.
• Ensure compliance with regulatory guidelines by maintaining SOPs, policies, and study documentation, and providing staff training and support.

Qualifications & Experience

Required:

• Strong knowledge of analytical techniques and hands-on experience with LC/MS and GxP principles (GLP, GCP, GMP, GCLP).
• Proficient with advanced instruments (e.g., Mass Spectrometry).
• Master\'s degree in a natural science or 5+ relevant experience.
• Proficient in following protocols, and using standard equipment (centrifuges, biosafety cabinets, incubators).
• Good command of written and spoken English, with strong collaboration and negotiation skills.

Desirable:

• Experience in GxP-accredited labs.
• Willingness to travel as needed.

PLEASE ENSURE THAT YOUR CV/RESUME IS SUBMITTED IN ENGLISH.