Senior Scientist II, Ex Vivo Electrophysiology

ZipRecruiter; Cambridge; On-site; GBP 50,000 - 80,000; Full time

Job summary

A leading company is seeking an experienced electrophysiologist to contribute to innovative drug discovery in psychiatry. This role involves conducting cutting-edge research on synaptic and circuitry dysfunction, requiring extensive expertise in electrophysiological techniques. The candidate will work collaboratively across teams, influencing the direction of research and guiding junior scientists in a dynamic environment.

Benefits

Comprehensive benefits package

Paid time off

401(k) eligibility

Short-term incentive programs

Long-term incentive programs

Qualifications

• PhD, MS, or BS in neuroscience or related field required.
• Typically requires 4+ (PhD), 10+ (MS), or 12+ (BS) years of experience.
• Extensive experience in electrophysiology and data processing.

Responsibilities

• Conceive and execute technical ideas related to electrophysiology.
• Drive electrophysiology efforts to investigate circuit function.
• Present findings to teams and contribute to strategic decision-making.

Skills

Whole-cell patch-clamp electrophysiology

Data processing and interpretation

Cross-functional team collaboration

Education

PhD in neuroscience

MS in neuroscience

BS in neuroscience

Job description

Job DescriptionJob DescriptionCompany Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

Job Description

AbbVie is seeking an experienced and highly motivated electrophysiologist to join our Circuit Biology team within Discovery Psychiatry. This pivotal role involvesfacilitating in vitro and ex vivo electrophysiological insights of circuit biology to drive our understanding of synaptic and circuit dysfunction in psychiatric disorders and treatment. This is an excellent opportunity to work at the forefront of psychiatry drug discovery research, contributing to target validation and compound profiling studies within a dynamic and collaborative team.

Key Responsibilities

• Independently conceive, execute, and communicate original technical ideas and novel multi-disciplinary research that achieves project and area goals
• Drive internal electrophysiology efforts by developing and optimizing disease-relevant in vitro andex-vivo experiments to investigate synaptic and circuit function
• Develop and maintain slice electrophysiology technology, methodology, and utility in psychiatric drug discovery
• Generate, through lab-based activities, slice electrophysiology data to support projects
• Ensure alignment of electrophysiology efforts with the broader goals of cross-functional teams
• Present findings to internal teams and external collaborators or conferences
• Contribute to strategic decision-making in psychiatry drug discovery
• Provide scientific guidance and training to junior scientists and research associates
• Serve as a lead scientist on projects and contribute scientific insights across multiple other project teams

Qualifications

• PhD, MS, or BS in neuroscience, or related field, with typically 4+ (PhD), 10+ (MS) or 12+ (BS) years of experience
• Extensive experience in whole-cell patch-clamp electrophysiology in acute brain slices, in vitro and ex vivo slice electrophysiology
• Extensive experience using slice electrophysiology to study intact circuitry from striatal, cortical and hippocampal networks
• Demonstrated expertise in the design and execution of hypothesis-driven studies related to synaptic and circuit function
• Ability to process and interpret large datasets using appropriate software tools
• Strong ability to work in cross-functional teams and effectively communicate scientific findings

Desired Qualifications

• Previous industry experience within early discovery, preferably within psychiatry research
• Expertise in ion channel drug discovery
• Recognized and sought out as an expert in field or discipline
• Track record of impactful publications

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

• This job is eligible to participate in our short-term incentiveprograms.

• This job is eligible to participate in our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

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https://www.abbvie.com/join-us/reasonable-accommodations.html