Senior Scientist I (Biologics Design, Production & Characterization)

Cyprotex; Alderley Edge; On-site; GBP 70,000 - 90,000; Full time

Benefits offered by this job

Pension scheme

Holiday entitlement

Private health insurance

Wellbeing support

Discretionary bonus

Career progression

Cycle-to-work scheme

Refer a friend scheme

Job summary

Evotec, located at Alderley Park, is seeking a Senior Scientist I in Biologics Design, Production and Characterization. The role focuses on designing and delivering high-quality biologics workflows and supporting multiple projects across teams.

The successful candidate will lead experimental design, data analysis, and communicate results to clients and stakeholders, contributing to Evotec’s scientific leadership and development of novel therapeutics.

Qualifications

• Strong biologics discovery and engineering expertise with timely delivery.
• Experience designing expression, purification and characterization workflows.
• Experience with lead optimisation including affinity maturation and manufacturability.
• Experience with using in silico-based tools for sequence and structural analysis is desirable.

Responsibilities

• Design and execution of agreed work plans for biologics engineering, design, production and characterization.
• Responsible for supporting multiple projects and may direct internal resources to achieve goals.
• Provide oversight of results to ensure quality to project specifications.
• Presents and publishes as appropriate peer-reviewed science increasing Evotec’s reputation.

Skills

Biologics design

Expression optimization

Purification workflows

High throughput

Lead optimisation

In silico tools

Data analysis

Team leadership

Education

PhD in relevant discipline

Tools

In silico tools

High-throughput methods

Job description

Job Title:

Senior Scientist I (Biologics Design, Production and Characterization)

Job Type:

Permanent

Location:

Alderley Park, Macclesfield, SK10 4TG

Our Company

Evotec is a leader in the discovery and development of novel small molecule drugs with operational sites in Europe and the US. The Company has built substantial drug discovery expertise and an industrialised platform that can drive new innovative small molecule compounds into the clinic. In addition, Evotec has built a deep internal knowledge base in the treatment of diseases related to neuroscience, pain, oncology, inflammation and metabolic diseases. Leveraging these skills and expertise the Company intends to develop best-in-class differentiated therapeutics and deliver superior science-driven discovery alliances with pharmaceutical and biotechnology companies

Key Accountabilities

• Design and execution of agreed work plans for biologics engineering, design, production and characterization.
• Responsible for supporting multiple projects and may be asked to direct internal resources to achieve agreed goals.
• Will be expected to provide oversight of results to ensure quality to project specifications.
• Accountable, together with project counterparts, for the design of experiment, review of documentation and client presentations. Will conduct thorough data analysis ahead of product release to internal or external customers.
• Proposes experimental designs and novel approaches to identify/advance best strategies in addition to planning/ executing project deliverables.
• Responsible for the implementation of standalone scientific services and deliverables to customers.
• Where responsible for reports will lead colleagues to co-develop plans for personal growth, aligned to business need.
• Represent the company at scientific and/or business conferences.
• Presents and publishes as appropriate peer-reviewed science increasing own and Evotec’s scientific reputation.

Knowledge & Experience

• Strong technical knowledge of biologics discovery and engineering with a proven ability to design and deliver results within agreed timelines and budget, meeting agreed quality criteria.
• Experience in the design and optimisation of expression, purification and characterisation workflows to deliver high-quality material and data for complex biologics (e.g. multi-specific antibodies, TCRs).
• Experience in high throughput methodology with associated data capture and handling.
• Experience in lead optimisation including affinity maturation, humanisation and manufacturability.
• Experience with using in silico-based tools for sequence and structural analysis is desired.
• Experience of preparing and executing workplans and building trusted partnership with internal and external customers.
• Requires a track record of leading scientists across specialist fields.
• Requires a track record of facilitating employee growth through co-development of PDP.
• Track record of successful problem-solving, high-quality science and influencing of stakeholders and colleagues.
• Experience of scientific development and research work ideally with publications in a relevant scientific field.

Education and Qualifications

Ideally a Ph.D. degree or corresponding experience in a relevant scientific discipline with relevant experience within industry. Alternatively, a relevant first degree and several years additional experience in drug discovery.

Evotec Leadership Competencies

Active Communication: Communicates actively, working on further clarity and responsiveness

Constructive Feedback: Actively seeks and provides constructive feedback, using it to improve processes and outcomes

Consistent Team Engagement: Engages frequently, fostering a more positive and collaborative environment

Foundational Direction Sharing: Communicates pragmatic directions, leading to general understanding and alignment

Occasional Planning: Begins anticipating problems and improves on proactively taking precautions

Effective Delegation: Delegates tasks effectively, trusting team members to handle responsibilities and providing necessary support and development

Benefits Package

• Pension on completion (but not subject to) of your 3-month probationary period. Contributions 5% for employees (salary sacrifice) and 5% for the employer. The employee can opt to increase their contribution, and the employer will match the increase up to a maximum of 7.5%.
• 25 days holiday plus bank holidays and additional length of service days awarded on the anniversary, up to a maximum of 30 days
• Private health insurance with BUPA for the employee and their partner/family under the company scheme
• Well being support 24/7 and counselling services
• Permanent health insurance provides 75% of the base salary after the qualifying period
• Private dental cover, on completion (but not subject to) of your 3-month probationary period
• Eligibility to participate in the Company Bonus Scheme. This is a discretionary benefit.
• Career progression within the company, we have excellent training and support and continuing professional development opportunities
• Cycle-to-work scheme
• Refer a friend scheme, team and annual events, recognition awards and many more!

Onsite Facilities

• The company pays for secure onsite parking
• Restaurant, Café, and Gastro pub
• Gym and workout studio, running, walking, and cycling routes
• Good public transport links with the shuttle bus service.

***Please note closing date for all applications will be Thursday 9th July 2026***

We may close this earlier depending on the number of applications received

FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.

ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.